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Syndecan-1 in the Serum of Deceased Kidney Donors as a Potential Biomarker of Kidney Function.
Transplant Proc
January 2025
Charles University, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic; Department of Anaesthesiology and Intensive Care, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; Faculty of Health Studies, Technical University in Liberec, Liberec, Czech Republic.
Background: The process of kidney transplantation remains the optimal treatment for end-stage renal disease, offering improved quality of life and increased survival rates compared to long-term dialysis. However, despite advances in surgical techniques, immunosuppression regimens, and post-operative care, there are still significant challenges in predicting the organ's status and long-term outcomes of transplantation. Among the many factors that influence graft survival, the quality of the donated organ plays a fundamental role.
View Article and Find Full Text PDFArterial compliance (AC) is an important cardiovascular parameter characterizing mechanical properties of arteries. AC is significantly influenced by arterial wall structure and vasomotion, and it markedly influences cardiac load. A new method, based on a two-element Windkessel model, has been recently proposed for estimating AC as the ratio of the time constant T of the diastolic blood pressure decay and peripheral vascular resistance derived from clinically available stroke volume measurements and selected peripheral blood pressure parameters which are less prone to peripheral distortions.
View Article and Find Full Text PDFEfficacy of non-surgical mechanical debridement with and without adjunct antimicrobial photodynamic therapy in the treatment of peri-implantitis among patients undergoing chemotherapy.
Photodiagnosis Photodyn Ther
January 2025
Department of Oral Maxillofacial Radiologist, Department of OMFS & DOS College of Medicine and Dentistry, Riyadh Elm University, Saudi Arabia.
Article Synopsis
- The study aimed to evaluate the effectiveness of antimicrobial photodynamic therapy (aPDT) combined with mechanical debridement (MD) in treating peri-implantitis in patients undergoing chemotherapy compared to systemically healthy patients.
- Both patient groups were assessed; however, results showed no significant differences in key measurements (plaque and gingival indices, probing depth, and bone loss) between the two groups at both baseline and three-month follow-up.
- Overall, the findings indicated that adding aPDT to MD did not lead to enhanced treatment outcomes for peri-implantitis in either chemotherapy patients or systemically healthy individuals.
A Lu-nucleotide coordination polymer-incorporated thermosensitive hydrogel with anti-inflammatory and chondroprotective capabilities for osteoarthritis treatment.
Biomaterials
January 2025
Department of Nuclear Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, China; Key Laboratory of Biological Nanotechnology, NHC, No. 87 Xiangya Road, Changsha, Hunan, 410008, China. Electronic address:
Osteoarthritis (OA) is a prevalent and debilitating condition characterized by cartilage destruction and inflammation. Traditional pharmacotherapies for OA are limited by their short-term efficacy and systemic side effects. Radiosynoviorthesis (RSO), involving intra-articular injection of radiopharmaceuticals, has shown promise for OA treatment but is hindered by the toxicity and rapid clearance of radioisotopes.
View Article and Find Full Text PDFSerial Procalcitonin Measurements for Determining Bacterial Infection and Mortality in Cirrhotic Patients with Systemic Inflammatory Response Syndrome.
Clin Transl Gastroenterol
December 2024
Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Introduction: The utility of serial procalcitonin (PCT) measurements in cirrhotic patients with systemic inflammatory response syndrome (SIRS) is not well understood. This study aimed to assess the effectiveness of serial PCT measurements for diagnosing bacterial infections and predicting 30-day mortality in this population.
Methods: We prospectively studied 120 cirrhotic patients with SIRS, 64.
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