Bilateral Gonadoblastoma Overgrown by Dysgerminoma of the Right Gonad in a Patient with Swyer Syndrome.

Maedica (Bucur)

Histopathology Training Program, Oman Medical Specialty Board, Muscat, Oman.

Published: December 2021

Patients with Swyer syndrome, "XY gonadal dysgenesis", have fibrosed gonads with a significant risk of developing germ cell tumours. During radiological assessment, a 17-year-old female with Swyer syndrome showed mildly enlarged gonads that were removed laparoscopically and proved pathologically to be bilateral gonadoblastomas. In addition, the right sided lesion showed overgrowth by dysgerminoma. The patient was further treated with combination chemotherapy and she was in complete remission for three years.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897794PMC
http://dx.doi.org/10.26574/maedica.2020.16.4.734DOI Listing

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