Purpose: To analyze the histopathological changes in eyelash following electroepilation using radiofrequency (RF) cautery.
Methods: RF current was applied to the eyelash root in human eyelids (from exenteration or eyelid shortening procedures) at a pre-determined depth of 3 mm excision a-priori, and processed for routine histology. Studied parameters were the extent of necrosis, involvement of the eyelash bulb, and type of bulb damage (partial or whole necrosis). Also, seven patients of chronic cicatrizing conjunctivitis with trichiasis ( = 4) and distichiasis ( = 3) underwent electroepilation using the above RF protocol.
Results: Twelve eyelid specimens of seven patients (mean age 40 years; five upper eyelid and seven lower eyelid) were evaluated histologically. Majority of specimens (92%) showed coagulative necrosis in the eyelash bulb, follicle, orbicularis oculi, adjacent nerves, and blood vessels. The mean depth of necrosis was 2.12 ± 0.63 mm. Of 12, eleven eyelash bulbs showed necrotic changes with only partial bulb involvement in 55% of eyelids. The horizontal extent of coagulative necrosis was not uniform across the lash track, and the majority showed a wider area of damage in the lower segment. Of seven, all patients with trichiasis (4/4) showed no recurrence of lash misdirection whereas 66% of distichiasis patients (2/3) showed recurrent lash growth with one sitting of electroepilation applied at 3 mm.
Conclusions: Electroepilation guided by RF current produces variable necrotic changes in the eyelash root, leaving portions of intact bulbs in half of the eyelids.
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http://dx.doi.org/10.1080/02713683.2022.2052107 | DOI Listing |
Ophthalmic Epidemiol
December 2024
Department of Ophthalmology and Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Purpose: To report the design of FLuorometholone as Adjunctive MEdical therapy for TT surgery (FLAME) trial.
Design: Parallel design, double-masked, placebo-controlled clinical trial with 1:1 randomization to fluorometholone 0.1% eye drops twice daily or placebo twice daily for 4 weeks in eyes undergoing trachomatous trichiasis (TT) surgery for assessing the efficacy, safety, and cost-effectiveness of fluorometholone 0.
Cutan Ocul Toxicol
December 2024
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Drug Des Devel Ther
November 2024
Department of Anesthesiology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, People's Republic of China.
Br J Dermatol
October 2024
Pfizer Inc, Paris, France.
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