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Time order errors have been investigated in several fields, and the time delay between subsequent stimuli in discrimination tasks is one example of such errors. However, the effect of these types of errors in thermal discrimination tasks is understudied. To evaluate the effect of inter-stimulus interval (ISI) on thermal perception, we used a discrimination task with a staircase method between two non-zero thermal stimuli. We found that JND was 3.10 and increased by 11.9% and 21.2% at JND and JND , respectively. Statistical analysis revealed that ISI was a statistically significant effect ( ) on thermal perception in our task. Future studies on thermal perception should keep the ISI consistent and report the time.
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http://dx.doi.org/10.1109/TOH.2022.3156122 | DOI Listing |
Toxicol Rep
June 2025
Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Iran.
Lead exposure is a significant environmental health concern with potential impacts on pain perception and physiological functions. This study investigates the effects of sub-chronic lead acetate exposure on pain threshold, pain intensity, blood cortisol levels, and metabolic parameters in 24 adult male albino mice. The mice were randomly divided into three groups: a control group that received fresh water and two experimental groups that received drinking water containing lead acetate at concentrations of 5 ppm and 500 ppm over a twelve-week period.
View Article and Find Full Text PDFBMC Womens Health
March 2025
Basic Health International, San Salvador, El Salvador.
Background: Cervical cancer remains a leading cause of cancer death for women worldwide. Screen-and-treat programs are a key strategy to reduce disease burden in low and middle-income countries (LMICs). Thermal ablation (TA) has emerged as a portable alternative to cryotherapy, the treatment typically used in screen-and-treat initiatives.
View Article and Find Full Text PDFSci Adv
March 2025
Center of Functionally Integrative Neuroscience (CFIN), Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
The human brain has a remarkable ability to learn and update its beliefs about the world. Here, we investigate how thermosensory learning shapes our subjective experience of temperature and the misperception of pain in response to harmless thermal stimuli. Through computational modeling, we demonstrate that the brain uses a probabilistic predictive coding scheme to update beliefs about temperature changes based on their uncertainty.
View Article and Find Full Text PDFCommun Biol
March 2025
Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Neuropathic pain involves complex cortical mechanisms, yet the role of the medial secondary visual cortex (V2M) remains poorly understood. We hypothesized that glutamatergic neurons in V2M (V2M) contribute to pain modulation and explored their functional involvement in both normal and neuropathic pain states. Here, we found that V2M could be activated by peripheral stimulation under normal conditions.
View Article and Find Full Text PDFInt J Biometeorol
March 2025
Departamento de Construção Civil, Universidade Tecnológica Federal do Paraná - UTFPR /Campus Curitiba - Sede Ecoville, Rua Deputado Heitor Alencar Furtado, 4900, Curitiba, 81280-340, Brazil.
Studies point to an increase in the frequency of heatwaves, revealing that they are longer lasting and more intense, with noticeable impacts from climate change observed in the south of Brazil. This study evaluates the impact of a heatwave event in Curitiba, Brazil, and investigates whether the excessive heat caused during this period influenced the thermal perception reported by participants in a fieldwork carried out during dynamic microclimatic surveys on a university campus. To this end, volunteers took part in thermal walks accompanied by a researcher carrying a portable equipment for monitoring environmental variables, covering points of interest previously defined in a walking circuit with different morphological and land cover configurations.
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