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Desensitization to drugs in children. | LitMetric

Desensitization to drugs in children.

Allergol Immunopathol (Madr)

Department of Child and Adolescent, Geneva University Hospitals, Geneva, Switzerland.

Published: April 2022

AI Article Synopsis

  • There is a lack of research on drug desensitization in children, leading to protocols being adapted from adult practices.
  • The article provides a review of the mechanisms, diagnostic tools, and current management strategies for drug hypersensitivity reactions specifically in the pediatric population.
  • It covers various types of hypersensitivity reactions related to chemotherapy, biologic agents, antibiotics, NSAIDs, and vaccines in children.

Article Abstract

Better knowledge and understanding about drug desensitization is required in the pediatric population, since there is little literature available about it and the most pediatric desensitization protocols have been adapted from adult instructions.Aiming to soften this issue and foster the future studies, this article presents a recent review about mechanisms of desensitization, diagnostic tools, and up to date management of drug hypersensitivity reactions in children. Bringing up an overview of pediatric hypersensitivity reactions to chemotherapy, biologic agents, antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines.

Download full-text PDF

Source
http://dx.doi.org/10.15586/aei.v50i2.539DOI Listing

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