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Influence of vascular imaging acquisition at local stroke centers on workflows in the drip-n-ship model: a RACECAT post hoc analysis.
J Neurointerv Surg
January 2024
Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
Article Synopsis
- The study investigates the impact of vascular imaging (VI) on patient workflows at local stroke centers (LSCs) in managing large vessel occlusion (LVO) strokes, using data from the RACECAT Trial.
- It compares outcomes for patients with and without VI upon arrival at LSCs, focusing on transfer rates, thrombectomy candidacy, and workflow times.
- Results indicate that VI acquisition leads to fewer unnecessary transfers and improved outcomes in thrombectomy procedures, suggesting its potential benefits need further research across different settings.
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity.
Proc Natl Acad Sci U S A
October 2013
Departments of Medicine and Pathology, University of California, San Diego, La Jolla, CA 92093.
Metronidazole and other 5-nitroimidazoles (5-NI) are among the most effective antimicrobials available against many important anaerobic pathogens, but evolving resistance is threatening their long-term clinical utility. The common 5-NIs were developed decades ago, yet little 5-NI drug development has since taken place, leaving the true potential of this important drug class unexplored. Here we report on a unique approach to the modular synthesis of diversified 5-NIs for broad exploration of their antimicrobial potential.
View Article and Find Full Text PDFEpidemiology and outcome of infections in human immunodeficiency virus/hepatitis C virus-coinfected liver transplant recipients: a FIPSE/GESIDA prospective cohort study.
Liver Transpl
January 2012
Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona.
Information about infections unrelated to acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV)-infected liver recipients is scarce. The aims of this study were to describe the prevalence, clinical characteristics, time of onset, and outcomes of bacterial, viral, and fungal infections in HIV/hepatitis C virus (HCV)-coinfected orthotopic liver transplant recipients and to identify risk factors for developing severe infections. We studied 84 consecutive HIV/HCV-coinfected patients who underwent liver transplantation at 17 sites in Spain between 2002 and 2006 and were followed until December 2009.
View Article and Find Full Text PDF[Indications and results of transanal endoscopic microsurgery in the treatment of rectal tumours in a consecutive series of 52 patients].
Cir Esp
October 2011
Servicio de Cirugía General y del Aparato Digestivo, Hospital Torrecárdenas, Almería, España.
Introduction: The abdominal approach for the treatment of rectal tumours is associated with considerable morbidity. Transanal endoscopic microsurgery (TEM) is a technical alternative, and less invasive than radical surgery, and thus, with a lower associated morbidity. Also, with the correct selection of patients, TEM shows similar oncological results to radical surgery.
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