AI Article Synopsis
- - A 25-year-old woman experienced severe breathing difficulties and tests showed she had a mixed restrictive and obstructive lung pattern, leading doctors to suspect a rare condition.
- - Imaging studies revealed a mosaic pattern in her lungs, and bronchoscopic samples helped confirm she had idiopathic obliterative bronchiolitis (OB), meaning there were no known underlying causes for her condition.
- - Given the severity of her disease, she was recommended for a lung transplant and referred to a specialized hospital for evaluation and potential surgery.
Article Abstract
Idiopathic obliterative bronchiolitis (OB) is a rare disease that usually requires a surgical lung biopsy. A 25-year-old woman with progressive exertional dyspnea for several months showed a severe mixed restrictive and obstructive pattern on spirometry. Chest computed tomography showed a mosaic pattern, and pulmonary ventilation-perfusion scintigraphy showed a matched defect. The bronchoscopic specimens obtained from both the alveolar and bronchiolar regions of the predicted lesion area contributed to the diagnosis of OB. She had no underlying causes of secondary OB, and she was diagnosed with idiopathic OB. Since lung transplantation was indicated, she was referred to a lung transplantation-certified hospital.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556245 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.8490-21 | DOI Listing |
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