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Optimizing growth in pediatric renal transplant recipients: An update.
World J Transplant
December 2024
Department of Paediatrics, Faculty of Medicine, University of Colombo, Colombo 0094, Sri Lanka.
Growth retardation is a significant complication observed in pediatric renal transplant recipients, originating from a multifactorial etiology. Factors contributing to growth impairment encompass pre-transplant conditions such as primary kidney disease, malnutrition, quality of care, growth deficits at the time of transplantation, dialysis adequacy, and the use of recombinant human growth hormone. Additionally, elements related to the renal transplant itself, such as living donors, corticosteroid usage, and graft functioning, further compound the challenge.
View Article and Find Full Text PDFSupplementation with a Whey Protein Concentrate Enriched in Bovine Milk Exosomes Improves Longitudinal Growth and Supports Bone Health During Catch-Up Growth in Rats.
Nutrients
November 2024
Abbott Nutrition R&D, Abbott Laboratories, 18004 Granada, Spain.
Background: Undernutrition impairs linear growth while restoration of nutritional provisions leads to accelerated growth patterns. However, the composition of the nutrition provided is key to facilitating effective catch-up growth without compromising bone quantity, quality, and long-term health.
Methods: We evaluated the role of a whey protein concentrate enriched in bovine milk exosomes (BMEs) in modulating the proliferative properties of human chondrocytes in vitro and studied how these effects might impact bone quantity and quality measured as longitudinal tibia growth, bone mineral content (BMC) and density (BMD), and trabecular micro-CT parameters in stunted rats during catch-up growth.
Maternal Perceptions and Feeding Practices Associated with Infant Nutritional Status.
Matern Child Health J
November 2024
Faculty of Biological Sciences, Universidad Autónoma de Nuevo León, Av. Pedro de Alba s/n, Ciudad Universitaria, San Nicolás de los Garza, Monterrey, 66450, México.
Article Synopsis
- Malnutrition in early childhood can lead to long-term health issues, including obesity, with this study focusing on how maternal perceptions and feeding practices influence infant nutrition in northeastern Mexico.
- The research assessed 192 mother-infant pairs, revealing that 38% of infants were overweight/obese while 7% were underweight, and identified key maternal factors like low self-efficacy and inaccurate weight perceptions affecting infant nutritional status.
- Findings suggest that many mothers lack knowledge about proper feeding practices, with longer sleep duration linked to underweight infants and critical inaccuracies in maternal perceptions of their child’s weight for both underweight and overweight/obese infants.
The effect of nutritional risk management program on the growth and development of infants and toddlers with congenital heart disease after discharge.
Front Pediatr
August 2024
Department of Cardiac Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), Fuzhou, China.
Article Synopsis
- The study aimed to assess how a nutritional risk management program affects the growth and development of infants and toddlers with congenital heart disease (CHD) after they leave the hospital.
- The research involved comparing two groups: one that received the nutritional program along with regular follow-up and another that only got traditional follow-up.
- Results showed that the intervention group had better growth outcomes and a lower rate of hospital readmissions compared to the control group, suggesting that the nutritional program is beneficial for these patients.
Effect of Gender on Metabolic and Neurodevelopmental Parameters of Postnatally Growth-Restricted Rats Undergoing Catch-Up Growth.
J Coll Physicians Surg Pak
September 2024
Department of Physiology, CMH Multan Institute of Medical Sciences, Multan, Pakistan.
Objective: To determine the long-term effects of early postnatal malnutrition and various degrees of catch-up growth on metabolic (serum glucose, leptin, triacylglycerides) and neurodevelopmental parameters (learning and memory) among male and female rodent models, mimicking human preterm infants.
Study Design: Randomized controlled trial. Place and Duration of the Study: CMH Multan Insitute of Medical Sciences, from September 2021 to December 2021.
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