AI Article Synopsis
- - Cerebral toxoplasmosis can be fatal for immunocompromised patients because it's often diagnosed and treated too late, with brain imaging revealing multiple rim-enhancing lesions to help differentiate it from other conditions.
- - In Korea, where cases are rare, delayed diagnosis and treatment of cerebral toxoplasmosis were observed in a male patient who developed the condition 21 years after a kidney transplant.
- - An open brain biopsy confirmed the diagnosis through immunohistochemistry and PCR analyses, but despite medication, the patient ultimately died from sepsis and recurrent gastrointestinal bleeding.
Article Abstract
Cerebral toxoplasmosis is often life-threatening in an immunocompromised patient due to delayed diagnosis and treatment. Several differential diagnoses could be possible only with preoperative brain images of cerebral toxoplasmosis which show multiple rim-enhancing lesions. Due to the rarity of cerebral toxoplasmosis cases in Korea, the diagnosis and treatment are often delayed. This paper concerns a male patient whose cerebral toxoplasmosis was activated 21 years post kidney transplantation. Brain open biopsy was decided to make an exact diagnosis. Cerebral toxoplasmosis was confirmed by immunohistochemistry and PCR analyses of the tissue samples. Although cerebral toxoplasmosis was under control with medication, the patient did not recover clinically and died due to sepsis and recurrent gastrointestinal bleeding.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898645 | PMC |
| http://dx.doi.org/10.3347/kjp.2022.60.1.35 | DOI Listing |
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