Revisiting Intracavitary Immunotherapy of Cancer.

Clin Cancer Res

Immunology and Immunotherapy Research Program, Cima Universidad de Navarra, Pamplona, Navarra, Spain.

Published: May 2022

AI Article Synopsis

  • Ovarian cancer frequently spreads within the peritoneal cavity, known as peritoneal carcinomatosis.
  • This localized spread allows for targeted delivery of immunotherapy treatments directly to the affected area, which can increase the effectiveness of the drugs.
  • This approach may minimize the side effects typically associated with systemic treatment methods.

Article Abstract

Ovarian cancer is often limited to the peritoneal cavity in the form of peritoneal carcinomatosis. Peritoneal spreading offers the opportunity for locoregional delivery of combinations of immunotherapy agents, maximizing bioavailability while potentially reducing systemic exposure and side effects. See related article by Orr et al., p. 2038.

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Source
http://dx.doi.org/10.1158/1078-0432.CCR-22-0201DOI Listing

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