Cross-species microRNA transmission modulates flavivirus growth in mosquitoes.

Trends Parasitol

Department of Microbiology & Immunology, Stanford University SOM, Stanford, CA 94305, USA. Electronic address:

Published: May 2022

Mosquitoes can be infected with a variety of RNA viruses. Recently,Zhu et al. demonstrated that human microRNA hsa-miR-150-5p is acquired by mosquitoes during blood meals and protects the Dengue virus by downregulation of chymotrypsin AaCT-1 mRNA. This finding suggests the use of microRNA antagomirs as an antiviral approach in mosquitoes.

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Source
http://dx.doi.org/10.1016/j.pt.2022.02.007DOI Listing

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