AI Article Synopsis
- The study investigates how globalization and increased international travel contribute to the importation of respiratory infectious diseases (RIDs) in China, using data from 2014 to 2018.
- It found that over 31,000 cases of imported RIDs were reported during this period, mostly comprised of influenza, with a notable increase in incidence rates over the years.
- The findings highlight the need for enhanced surveillance and high-tech methods to detect and prevent the spread of imported RIDs to safeguard public health in China.
Article Abstract
Background: With the progress of globalization, international mobility increases, greatly facilitating cross-border transmission of respiratory infectious diseases (RIDs). This study aimed to analyze the epidemiological characteristics and factors influencing imported RIDs, with the goal of providing evidence to support adoption of high-tech, intelligent methods to early find imported RIDs and prevent their spread in China.
Methods: We obtained data of imported RIDs cases from 2014 to 2018 from the Inbound Sentinel Network of Customs and the National Notifiable Diseases Reporting System in China. We analyzed spatial, temporal, and population distribution characteristics of the imported RIDs. We developed an index to describe seasonality. Pearson correlation coefficients were used to examine associations between independent variables and imported cases. Data analyses and visualizations were conducted with R software.
Results: From a total of 1 409 265 253 inbound travelers, 31 732 (2.25/100 000) imported RIDs cases were reported. RIDs cases were imported from 142 countries and five continents. The incidence of imported RIDs was nearly 5 times higher in 2018 (2.81/100 000) than in 2014 (0.58/100 000). Among foreigners, incidence rates were higher among males (5.32/100 000), 0-14-year-olds (15.15/100 000), and cases originating in Oceania (11.10/100 000). The vast majority (90.3%) of imported RIDs were influenza, with seasonality consistent with annual seasonality of influenza. The spatial distribution of imported RIDs was different between Chinese citizens and foreigners. Increases in inbound travel volume and the number of influenza cases in source countries were associated with the number of imported RIDs.
Conclusions: Our study documented importation of RIDs into China from 142 countries. Inbound travel poses a significant risks bringing important RIDs to China. It is urgent to strengthen surveillance at customs of inbound travelers and establish an intelligent surveillance and early warning system to prevent importation of RIDs to China for preventing further spread within China.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895356 | PMC |
| http://dx.doi.org/10.1186/s40249-022-00944-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Epidemiological characteristics of imported respiratory infectious diseases in China, 2014‒2018.
Infect Dis Poverty
March 2022
National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Article Synopsis
- The study investigates how globalization and increased international travel contribute to the importation of respiratory infectious diseases (RIDs) in China, using data from 2014 to 2018.
- It found that over 31,000 cases of imported RIDs were reported during this period, mostly comprised of influenza, with a notable increase in incidence rates over the years.
- The findings highlight the need for enhanced surveillance and high-tech methods to detect and prevent the spread of imported RIDs to safeguard public health in China.
Copper-zinc superoxide dismutase (Sod1) activation terminates interaction between its copper chaperone (Ccs) and the cytosolic metal-binding domain of the copper importer Ctr1.
Biometals
August 2019
Department of Biological Sciences, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA.
Copper-zinc superoxide dismutase (Sod1) is a critical antioxidant enzyme that rids the cell of reactive oxygen through the redox cycling of a catalytic copper ion provided by its copper chaperone (Ccs). Ccs must first acquire this copper ion, directly or indirectly, from the influx copper transporter, Ctr1. The three proteins of this transport pathway ensure careful trafficking of copper ions from cell entry to target delivery, but the intricacies remain undefined.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!