Dihydrophenanthrenes and phenanthrenes from .

Nat Prod Res

Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China.

Published: July 2023

Two previously undescribed dihydrophenanthrene derivatives ( and ) were isolated along with twelve known analogues from the whole plant of . The structures of the new compounds were elucidated on the basis of detailed spectroscopic analysis. The NMR data of known phenanthrene derivatives ( and ) were revised by 2D NMR. The isolated compounds were evaluated for cytotoxicity against three kinds of tumor cell lines (sw1990, HCT-116, and HepG2). Especially compounds and showed stronger antitumor effects, and the structure-activity relationship of these compounds was discussed.

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2022.2048379DOI Listing

Publication Analysis

Top Keywords

dihydrophenanthrenes phenanthrenes
4
phenanthrenes undescribed
4
undescribed dihydrophenanthrene
4
dihydrophenanthrene derivatives
4
derivatives isolated
4
isolated twelve
4
twelve analogues
4
analogues plant
4
plant structures
4
compounds
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!