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A 26-Year-Old Woman with Postpartum Abdominal Pain.
NEJM Evid
February 2025
from the Fellowship Program in Maternal-Fetal Medicine and the Sections of Infectious Diseases and Global Health and Gastroenterology, Hepatology, and Nutrition at the University of Chicago Medical Center.
AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry on this tradition by presenting a patient's chief concern and story, inviting the reader to develop a differential diagnosis and discover the diagnosis alongside the authors of the case. This report examines the story of a 26-year-old woman who developed acute hepatocellular liver injury following a cesarean delivery for fetal distress.
View Article and Find Full Text PDFDiabetes Management Using a Patient Navigator in a Native Hawaiian Population: Experiences and Perceptions of the Kilolani Project.
Int J Environ Res Public Health
January 2025
The Queen's Health System, Honolulu, HI 96813, USA.
Native Hawaiians (NHs) are a historically oppressed population disproportionately burdened by diabetes and related complications. The Kilolani Project, a patient navigator-centered, chronic disease management program, targets upstream drivers of health among vulnerable NH adult patients with diabetes within an urban academic safety-net clinic. To investigate the impact of the Kilolani Project, we performed a qualitative study to examine patient perspectives.
View Article and Find Full Text PDFQuality of life and return to work rates in the first two years following major burn injury.
Burns
December 2024
School of Public Health and Preventive Medicine, Monash University, Australia; Population Data Science, Swansea University, Wales.
Background: A better understanding of how major burns patients recover following injury is vital in assessing trauma care and informing healthcare and rehabilitation provision. We aimed to describe the longer-term health and return to work status of major burns patients and identify factors associated with positive outcomes i.e.
View Article and Find Full Text PDFClinical Swallow Examination Following Laryngectomy: An International e-Delphi Consensus Process.
Dysphagia
January 2025
Speech Pathology & Audiology Department, Royal Brisbane & Women's' Hospital, Level 2, Dr James Mayne Building, Butterfield Street, Herston, Brisbane, QLD, Australia.
Clinical swallow examination (CSE) following laryngectomy (± pharyngeal resection) remains a critical step in dysphagia evaluation. Whilst the core components of a standard CSE service a broad spectrum of patient populations, no evidence exists examining the essential assessment items specific to CSE in the laryngectomy population. The aim of this study was to identify the tasks, measures and observations considered necessary to include in a CSE post laryngectomy.
View Article and Find Full Text PDFInsights from animal studies exploring the efficacy and safety of topical losartan, in prophylaxis and treatment of corneal scarring fibrosis.
Biomed Pharmacother
January 2025
The Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 44195, United States. Electronic address:
Several studies in rabbits demonstrated the efficacy and safety of topical losartan, an angiotensin II receptor blockers (ARB) that modulates the TGF-β intracellular signaling pathways by inhibiting the activation of Extracellular Signal-regulated Kinase (ERK), in preventing or treating stromal fibrosis after a range of injuries such as Descemetorhexis, alkali burns, incisions, and photorefractive keratectomy (PRK). Several case reports have shown that topical losartan treatment is also efficacious and safe in humans to prevent or treat stromal fibrosis after many different injuries or diseases. Topical losartan penetrates the full thickness of the cornea and, therefore, can treat both anterior and posterior stromal fibrosis.
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