Background/aim: The purpose of this study was to determine whether a semi-cylindrical beam spoiler (sCBS) developed herein effectively increases the skin dose in patients with early-stage glottic cancer.
Patients And Methods: We measured the surface doses for 26 patients who used the sCBS during treatment of early-stage glottic cancer through a parallel-opposed lateral two-field 6 MV photon beam. Measurements were performed by attaching optically stimulated luminescent dosimeters to the left, right, anterior (in-field), inferior, and superior (out-field) sides of the patient.
Results: The measured results were 81.8±2.1% (left), 81.0±1.7% (right), and 76.8±2.7% (anterior) in the in-field region compared to prescription doses, with 5.7±1.7% (superior) and 2.7±0.7% (inferior) in the out-field region.
Conclusion: sCBS can deliver a suitably ideal surface dose for treatment of early-stage glottic cancer.
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http://dx.doi.org/10.21873/invivo.12795 | DOI Listing |
Eur Arch Otorhinolaryngol
December 2024
King Hussein Cancer Center, Medical Oncology Department, Amman, Jordan.
Purpose: Over the last 40 years, there has been an unusual trend where, even though there are more varied treatments, survival rates have not improved much. Our study used survival analysis and machine learning (ML) to investigate this odd situation and to improve prediction methods for treating non-metastatic LSCC.
Methods: The surveillance, epidemiology and end results (SEER) database provided the data used for this study's analysis.
Clin Otolaryngol
December 2024
Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle-Upon-Tyne, UK.
Introduction: Historically, 15% of laryngeal cancer patients undergo non-curative management, but pragmatic data on this group are limited. This information is crucial to help patients make informed decisions about their care. Supported by the Northern Head & Neck Alliance, this retrospective study is the first to present survival outcomes for non-curative laryngeal cancer patients in Northern UK.
View Article and Find Full Text PDFCureus
September 2024
First University Department of Otorhinolaryngology, Head and Neck Surgery, University of Athens, Hippocrateion Hospital, Athens, GRC.
Background and objective The treatment of early-stage laryngeal glottic cancer involves surgery or radiotherapy, and both have similar survival rates. However, discrepancies between systematic reviews in the literature point towards the continuous need for more data. In this study, we aimed to investigate the oncologic value of surgery at an ENT university department of a tertiary hospital in Greece.
View Article and Find Full Text PDFJ Cancer Res Ther
July 2024
Department of Radiation Oncology, Cancer Research Institute, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India.
Biomedicines
September 2024
Clinic for Otorhinolaryngology, Head and Neck Surgery, University Hospital Leipzig, Liebigstr. 10-14, 04103 Leipzig, Germany.
Laryngeal squamous cell carcinoma (LSCC) is among most frequent malignancies of the head and neck. Recent oncologic research focusses on advanced rather than on early stages. Thus, we aimed to improve the knowledge concerning prognostic factors and survival in early glottic (GC) and supraglottic cancer (SGC).
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