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Patient-reported quality of life and adherence outcomes after integrating exclusive liquid meal replacement in patients with head and neck cancer undergoing chemoradiation: results from a phase II study.
Front Oncol
January 2025
Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, United States.
Objectives: Preventing malnutrition during chemoradiation (CRT) for head and neck cancer is critical maximizing quality of life (QOL). We sought to assess patient-reported QOL outcomes after integrating exclusive liquid meal replacement with Soylent, a novel meal replacement agent, in patients with head and neck cancer undergoing CRT.
Methods: Patients undergoing definitive or adjuvant concurrent CRT for locally advanced head and neck cancer enrolled on our single-institution, prospective phase II protocol evaluating nutritional replacement with Soylent.
Advanced glycation end products and breast cancer risk in a sample of the ORDET cohort.
Int J Biol Markers
January 2025
Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Introduction: Breast cancer is the most common cancer among women, and metabolic syndrome (MetS) is a risk factor for breast cancer, especially postmenopausal breast cancer. We evaluated the role of the advanced glycated end products (AGEs) levels contributing to the association between MetS and breast cancer risk.
Methods: Plasma AGEs were measured in a case-control study nested within the Hormones and Diet in the Etiology of Breast Tumors (ORDET) cohort, including 40 incident postmenopausal breast cancer cases (20 with MetS and 20 without) and 40 postmenopausal controls (20 with MetS and 20 without).
A novel electronic nose for sensing (E)-2-hexenal based on Mn-MOF nanonets with NADPH-like activity.
Food Chem
January 2025
College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China; University Key Laboratory of Food Processing Byproducts for Advanced Development and High Value Utilization, Xi'an 710119, China. Electronic address:
Bioreceptors are increasingly popular for selective aroma sensing but face challenges with receptor separation and cell culture. Here, we developed a bioreceptor-free electronic nose employing Mn-metal organic framework (Mn-MOF) nanonets as sensing materials for rapid electrochemical quantification of (E)-2-hexenal, a characteristic aroma commonly found in various foods. A simple solvent-mediated morphology engineering technology was proposed to create Mn-MOF structures, including nanoparticles, nanowires, and nanonets.
View Article and Find Full Text PDFAssociation of steatotic liver disease with all-cause and cardiovascular mortality among prehypertensive or hypertensive patients.
J Glob Health
January 2025
School of Public Health and Emergency Management, School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Background: Prehypertension and hypertension often coexist with non-alcoholic fatty liver disease (NAFLD) during the progression of cardiovascular disease (CVD). International academic liver societies have recently reached a consensus to replace NAFLD with the new term 'steatotic liver disease' (SLD). In this study, we aimed to evaluate the impact of different SLD subtypes on all-cause and CVD mortality in individuals with prehypertension or hypertension.
View Article and Find Full Text PDFAssociation and mechanism of montelukast on sleep disorders: insights from NHANES 2005-2018 data analysis and a network pharmacology study.
J Asthma
January 2025
School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Background: Studies have suggested associations between montelukast and increased risks of sleep disorders, including overall sleeping problems and insomnia. However, the results of observational studies are not consistent. Understanding these associations is crucial, particularly in patients solely diagnosed with allergic rhinitis, where montelukast use remains prevalent.
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