Preprint servers allow rapid publication of research findings by eliminating the time gap between submission and publication associated with editorial and peer review of scientific works. Consequently, non-peer-reviewed articles are essentially accessible immediately to researchers and the public. There are many valid justifications for sharing work on preprint servers, such as the ability to collect feedback from the research community and improve work prior to journal submission and a reduced risk of work being "scooped" by competitors. Rapid access to the latest scientific developments can furthermore expedite progress in important research areas. Significant downsides of preprint servers, however, are that the public, including members of the media and policy makers, cannot judge the quality of such non-reviewed publications and that misinformation may be spread. Balancing the good and the bad of preprint servers as opposed to classic peer review, we provide guidance for authors of the Journal of Plant Physiology.
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http://dx.doi.org/10.1016/j.jplph.2022.153661 | DOI Listing |
Environ Sci Pollut Res Int
January 2025
Department of Agricultural Chemistry, National Taiwan University, Taipei, 106319, Taiwan.
Rare earth elements (REEs) are emerging contaminants rendering potential risks in soils to environmental quality and human health. The causation between their geochemical signatures and contamination levels with parent rocks and soil properties are critical for REEs risk assessments, which are urgently needed globally. Thus, this study aimed to elucidate cause-and-effect among hydrofluoric-acid-digested total and ethylenediaminetetraacetic acid extracted bioavailable soil REEs and their contamination degree evaluated by pollution indices in 268 soil layer (horizon) samples from 50 soil profiles derived from felsic, intermediate, mafic, ultramafic, and sedimentary rocks in Taiwan.
View Article and Find Full Text PDFThe ARID1A gene, frequently mutated in cancer, encodes the AT-rich interactive domain-containing protein 1A, a key component of the chromatin remodeling SWI/SNF complex. The ARID1A protein features a conserved DNA-binding domain (ARID domain) of approximately 100 residues crucial for its function. Despite the frequency of mutations, the impact on ARID1A's stability and contribution to cancer progression remains unclear.
View Article and Find Full Text PDFbioRxiv
December 2024
IFB-core, Institut Français de Bioinformatique, CNRS, INSERM, INRAE, CEA, Evry, France.
Microbial research generates vast and complex data from diverse omics technologies, necessitating innovative analytical solutions. microGalaxy (Galaxy for Microbiology) addresses these needs with a user-friendly platform that integrates >220 tool suites and >65 curated workflows for microbial analyses, including taxonomic profiling, assembly, annotation, and functional analysis. Hosted on the main EU Galaxy server (microgalaxy.
View Article and Find Full Text PDFMotivation: Artificial intelligence (AI) applications require explainability (XAI) for FAIR, ethical deployment, whether in the clinic or in the laboratory. Richly descriptive XAI metadata representing how pre-model data were obtained, characterized, transformed, and distributed, should be available along with the data prior to training and application of AI models.
Results: The FAIRSCAPE framework generates, packages, and integrates critical pre-model XAI descriptive metadata, including deep provenance graphs and data dictionaries with feature validation on uploaded data, software, and computations, with special reference to biomedical datasets.
BMC Surg
January 2025
Chongqing Nanping Aier Ophthalmology, 249 Nancheng Avenue, Nanan District, Chongqing, P. R. China.
Purpose: This study aims to examine the correlation between specific clinical parameters, such as axial eye length, and the onset of ocular hypertension "OH" following the use of silicone oil filling in patients with high myopia.
Method: In this retrospective analysis, we reviewed 214 eyes from 432 patients diagnosed with severe myopia, all of whom underwent vitrectomy and were treated with silicone oil filling. The study aimed to document the incidence and timing of postoperative ocular hypertension "OH" while assessing various factors, including demographic details, medical history, additional surgical interventions, and findings from supplementary examinations (such as axial length, silicone oil emulsification, and anterior chamber penetration).
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