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Adverse Events Associated With Endoscopic Retrograde Cholangiopancreatography: Systematic Review and Meta-Analysis.
Gastroenterology
November 2024
Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada. Electronic address:
Background & Aims: Endoscopic retrograde cholangiopancreatography (ERCP)-related adverse events (AEs) are associated with morbidity, mortality, and health care expenditure. We aimed to assess incidences and comparisons of ERCP AEs.
Methods: We included studies performed after 2000 reporting on ERCP AEs from database inception through March 12, 2024.
Observation of the decay.
Eur Phys J C Part Fields
October 2024
Authors affiliated with an institute or an international laboratory covered by a cooperation agreement with CERN, Geneva, Switzerland.
Using proton-proton collision data corresponding to an integrated luminosity of collected by the CMS experiment at , the decay is observed for the first time, with a statistical significance exceeding 5 standard deviations. The relative branching fraction, with respect to the decay, is measured to be , where the first uncertainty is statistical, the second is systematic, and the third is related to the uncertainties in and .
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- The study evaluated the effectiveness of palbociclib, a targeted cancer therapy, in patients with advanced cancer exhibiting specific genomic alterations, focusing on two patient groups: those with head and neck cancer (HNC) and those with a mix of histologies (HP).
- Results showed that 40% of the HNC patients achieved disease control, which was statistically significant, while only 13% of the HP cohort did, failing to meet the criteria for significance.
- The treatment had notable side effects, with over 40% of patients experiencing serious adverse events, primarily blood-related issues like neutropenia and thrombocytopenia.
Portable Acceleration of CMS Computing Workflows with Coprocessors as a Service.
Comput Softw Big Sci
September 2024
Authors affiliated with an institute or an international laboratory covered by a cooperation agreement with CERN, Geneva, Switzerland.
Article Synopsis
- Demand for computing power in major scientific experiments, like the CMS at CERN, is expected to significantly increase over the coming decades.
- The implementation of coprocessors, particularly GPUs, in data processing workflows can enhance performance and efficiency, especially for machine learning tasks.
- The Services for Optimized Network Inference on Coprocessors (SONIC) approach allows for improved use of coprocessors, demonstrating successful integration and acceleration of workflows across various environments without sacrificing throughput.
Introduction: Individuals living with Crohn's disease (CD) experience burdensome symptoms. As such, it is important to measure CD symptom severity in clinical research. The goal of this study was to evaluate the content validity, psychometric performance, and score interpretability of a new patient-reported instrument, the Crohn's Symptom Severity (CSS) questionnaire, among adolescents and adults with moderately to severely active CD.
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