Background: The aim of the present study is to evaluate the reliability of a F-fluorodeoxyglucose (F-FDG) PET adaptive threshold segmentation (ATS) algorithm, previously validated in a preclinical setting on several scanners, for the biological target volume (BTV) delineation of head and neck radiotherapy planning.
Methods: [18F]FDG PET ATS algorithm was studied in treatment plans of head and neck squamous cell carcinoma on a dedicated workstation (iTaRT, Tecnologie Avanzate, Turin, Italy). BTVs segmented by the present ATS algorithm (BTV
Results: The study was conducted on 32 treatment plans. Median BTV
Conclusions: ATS algorithm could be a smart and an independent operator tool when implemented for F-FDG-PET-based tumor volume delineation. Furthermore, it might be relevant in case of BTV-based dose painting.
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