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Lens Biometry Using the Novel Ultrasound Biomicroscopy. | LitMetric

Lens Biometry Using the Novel Ultrasound Biomicroscopy.

Front Med (Lausanne)

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.

Published: February 2022

Background And Aim: To assess the reproducibility of the novel ultrasound biomicroscopy, Insight 100 and its agreement with a swept-source optical coherence tomography, CASIA2.

Methods: A total of 96 volunteers (96 eyes) were enrolled. The radius of anterior lens curvature (RAL), the radius of posterior lens curvature (RPL), lens thickness (LT), and lens diameter (LD) were measured with Insight 100 and CASIA2. A semiautomated software was used to adjust the measurement of LT (LT) and LD (LD) by Insight 100. Intraobserver and interobserver reproducibility of Insight 100 measurements, and the agreement of results from Insight 100 and CASIA2 were assessed with 95% limit of agreement (LoA), intraclass correlation coefficient (ICC), Pearson correlation, and linear regression.

Results: For Insight 100 measurements, the intraobserver ICCs of RAL, RPL, LT, and LD measurement were 0.996, 0.973, 0.936, and 0.889, and the interobserver ICCs were 0.987, 0.890, 0.974, and 0.816, respectively. There was an excellent correlation in LT measurements ( = 0.961, < 0.001) but poor agreements in other parameters between the two devices. The LD measurements tended to be larger (95% CI: 0.768-0.928) in CASIA2 when compared with Insight 100.

Conclusion: Insight 100 could obtain highly repeatable lens biometry . With better signal penetration, it shows promising potential in future clinical applications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882853PMC
http://dx.doi.org/10.3389/fmed.2022.777645DOI Listing

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