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Immunological aspects of probiotics for improving skin diseases: Influence on the Gut-Brain-Skin Axis.
Biochem Biophys Res Commun
April 2024
Cellular and Molecular Research Center, Research Institute for Prevention of Non-Communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran. Electronic address:
The interplay between gut microbiota and human health, both mental and physical, is well-documented. This connection extends to the gut-brain-skin axis, linking gut microbiota to skin health. Recent studies have underscored the potential of probiotics and prebiotics to modulate gut microbiota, supported by in vivo and clinical investigations.
View Article and Find Full Text PDFImplication of the gut-brain-skin axis affecting the skin, and specifically C. acnes.
Int J Dermatol
May 2023
Department of Internal Medicine, University of Toledo College of Medicine, Toledo, OH, USA.
Comparative Analysis of the Microbiome across the Gut-Skin Axis in Atopic Dermatitis.
Int J Mol Sci
April 2021
College of Medicine, Kyung Hee University, Seoul 02447, Korea.
Atopic dermatitis (AD) is a refractory and relapsing skin disease with a complex and multifactorial etiology. Various congenital malformations and environmental factors are thought to be involved in the onset of the disease. The etiology of the disease has been investigated, with respect to clinical skin symptoms and systemic immune response factors.
View Article and Find Full Text PDFPsychosocial Stress and Mechanisms of Skin Health: A Comprehensive Update.
J Drugs Dermatol
January 2021
Although the relationship between psychosocial stress and skin health is commonly invoked in both the scientific and popular literature, its underlying mechanisms are still not well understood. In this review, we provide a comprehensive update on the pathophysiology of stress and its clinical impact on skin homeostasis. The recent characterization of a bidirectional HPA stress axis in the skin has illuminated peripheral stress pathways, with effects spanning inflammation, atopy, barrier function, dermal thinning, wound healing, and melanogenesis.
View Article and Find Full Text PDFThe Effect of Oral Probiotic on the Interleukin-10 Serum Levels of Acne Vulgaris.
Open Access Maced J Med Sci
October 2019
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia.
Background: Acne vulgaris is a chronic inflammatory skin disorder that commonly found in pilosebaceous units which can have an impact on the patient's psychological burden. The relationship between dermatology and mental health is increasingly understood by the evidence shows that functional integrity and microbes in the gastrointestinal tract may play a role in mediating skin inflammation and emotional behaviour. The gut-brain-skin theory was first described in 1930 by Stokes and Pillsbury, became the basis of many current studies that look for clinical implications of the relationship between the gastrointestinal tract, brain and skin in acne vulgaris.
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