Depression is the most incapacitating disease worldwide, and it has an alarming comorbidity rate with anxiety. The use of social networks to expose personal difficulties has enabled works on the automatic identification of specific mental conditions, particularly depression. In spite of many solutions proposed for the automatic recognition of depression, fewer exist for anxiety and its comorbidity with depression. In this paper, we propose DAC Stacking, a solution that leverages stacking ensembles and Deep Learning (DL) to automatically identify depression, anxiety, and their comorbidity, using data extracted from Reddit. The stacking is composed of single-label binary classifiers, that either distinguish between specific disorders and control users (experts), or between pairs of target conditions (differentiating). A meta-learner explores these base classifiers as a context for reaching a multi-label decision. We assessed alternative ensemble topologies, exploring roles for base models, DL architectures, and word embeddings. All base classifiers and ensembles outperformed the baselines for depression and anxiety (f-measures near 0.79). The ensemble topology with the best performance (Hamming Loss of 0.29 and Exact Match Ratio of 0.46) combines base classifiers of three DL architectures, and includes expert and differentiating base models. The analysis of the influential classification features according to SHAP revealed the strengths of our solution and provided insights on the challenges for the automatic classification of the addressed mental conditions.
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http://dx.doi.org/10.1109/JBHI.2022.3151589 | DOI Listing |
Funct Integr Genomics
January 2025
Department of Exercise Science and Health Promotion, Florida Atlantic University, Boca Raton, FL, USA.
Large-scale, pan-cancer analysis is enabled by data driven knowledge bases that link tumor molecular profiles with phenotypes. A debilitating cancer-related phenotype is skeletal muscle loss, or cachexia, which occurs partly from tumor products secreted into circulation. Using the LinkedOmicsKB knowledge base assembled from the Clinical Proteomics Tumor Analysis Consortium proteogenomic analysis, along with catalogs of human secretome proteins, ligand-receptor pairs and molecular signatures, we sought to identify candidate pan-cancer proteins secreted to blood that could regulate skeletal muscle phenotypes in multiple solid cancers.
View Article and Find Full Text PDFInt J Syst Evol Microbiol
January 2025
Dpartement de Biotechnologie, Laboratoire des Productions, Valorisations Vgtales et Microbiennes (LP2VM), Facult des Sciences de la Nature et de la Vie, B.P. 1505, El-Mnaour, Universit des Sciences et de la Technologie dOran Mohamed Boudiaf USTO-MB, Oran 31000, Algeria.
A thorough polyphasic taxonomic study, integrating genome-based taxonomic approaches, was carried out to characterize the RB5 strain isolated from root nodules of growing on the coastal dunes of Bousfer Beach (Oran, Algeria). The 16S rRNA gene sequence analysis revealed that strain RB5 had the highest similarity to LMG27940 (98.94%) and IzPS32d (98.
View Article and Find Full Text PDFInt J Syst Evol Microbiol
January 2025
Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato, Tokyo 108-8477, Japan.
A crude oil aggregation-forming, strictly anaerobic, Gram-stain-positive, spore-forming, rod-shaped, motile and mesophilic bacterium, named strain SH18-2, was isolated from marine sediment near Sado Island in the Sea of Japan. The temperature, salinity and pH ranges of this strain for the growth were 15-40 °C (optimum 35 °C), 0.5-6.
View Article and Find Full Text PDFInt J Syst Evol Microbiol
January 2025
Department of Biology, Slippery Rock University, Slippery Rock, Pennsylvania 16057, USA.
A polyphasic taxonomic study was carried out on strain T9W2-O, isolated from the roots of the aquatic plant . This isolate is rod-shaped, forms yellow/orange pigmented colonies and produces the pigment flexirubin. Nearly complete 16S rRNA gene sequence homology related the strain to , with 98.
View Article and Find Full Text PDFInt J Syst Evol Microbiol
January 2025
ABS Research Support Center, KRIBB, 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.
Two Gram-stain-negative cocci anaerobes were isolated from pig faeces and designated as strains YH-vei2232 and YH-vei2233. Phylogenetic analysis using 16S rRNA gene sequences revealed that the isolates were most closely related to KCTC 5967, with 97.0% similarity.
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