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Automated design prediction for definitive obturator prostheses: A case-based reasoning study.
J Prosthodont
January 2025
Department of Advanced Prosthodontics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Purpose: This study aims to evaluate the effectiveness of a case-based reasoning (CBR) system in predicting the design of definitive obturator prostheses for maxillectomy patients.
Materials And Methods: Data from 209 maxillectomy cases, including extraoral images of obturator prostheses and occlusal images of maxillectomy defects, were collected from Institute of Science Tokyo Hospital. These cases were organized into a structured database using Python's pandas library.
Exposure to childhood maltreatment is associated with specific epigenetic patterns in sperm.
Mol Psychiatry
January 2025
Institute of Biomedicine, Integrative Physiology and Pharmacology Unit, University of Turku, Turku, Finland.
Childhood maltreatment exposure (CME) increases the risk of adverse long-term health consequences for the exposed individual. Animal studies suggest that CME may also influence the health and behaviour in the next generation offspring through CME-driven epigenetic changes in the germ line. Here we investigated the associated between early life stress on the epigenome of sperm in humans with history of CME.
View Article and Find Full Text PDFVessel strike encounter risk model informs mortality risk for endangered North Atlantic right whales along the United States east coast.
Sci Rep
January 2025
Office of Protected Resources, NOAA Fisheries, Silver Spring, MD, 20910, USA.
Vessel strikes are a critical threat to endangered North Atlantic right whales (Eubalaena glacialis), significantly contributing to their elevated mortality. Accurate estimates of these mortality rates are essential for developing effective management strategies to aid in the species' recovery. This study enhances existing vessel strike models by incorporating detailed regional data on vessel traffic characteristics as well as whale distribution and behavior.
View Article and Find Full Text PDFAdolescent cerebellar nuclei manipulation alters reversal learning and perineuronal net intensity independently in male and female mice.
J Neurosci
January 2025
Arizona State University, Department of Psychology, Tempe, AZ, 85287 USA.
The cerebellum, identified to be active during cognitive and social behavior, has multisynaptic connections through the cerebellar nuclei (CN) and thalamus to cortical regions, yet formation and modulation of these pathways are not fully understood. Perineuronal nets (PNNs) respond to changes in local cellular activity and emerge during development. PNNs are implicated in learning and neurodevelopmental disorders, but their role in the CN during development is unknown.
View Article and Find Full Text PDFManagement of wind-turbine blade waste as high-content concrete addition: Mechanical performance evaluation and life cycle assessment.
J Environ Manage
January 2025
Department of Civil Engineering, Escuela Politécnica Superior, University of Burgos, c/ Villadiego s/n, 09001, Burgos, Spain. Electronic address:
The management of end-of-life wind-turbine blades in the coming years will be necessary, as a clear solution for their recycling is yet to be found due to their complex composition. The suitability of their mechanical recycling is therefore evaluated in this paper, obtaining Raw-Crushed Wind-Turbine Blade (RCWTB) for subsequent incorporation in high amounts of up to 10% vol. in concrete, replacing the aggregates to achieve Fiber-Reinforced Concrete (FRC).
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