AI Article Synopsis
- A 22-year-old woman was diagnosed with Graves' disease and thymic hyperplasia after being referred for evaluation of thyrotoxicosis and a thymic mass.
- After starting treatment with thiamazole, her thyroid function normalized within one month, while thymic size gradually decreased, normalizing after 12 months.
- There was a strong correlation between the levels of thyroid-stimulating hormone receptor antibodies and thymic size, indicating a potential link between her autoimmune condition and thymic hyperplasia.
Article Abstract
We treated a 22-year-old woman suffering from Graves' disease and thymic hyperplasia. She was referred to our institution for a close investigation of thyrotoxicosis and thymic mass. Thyroid tests and magnetic resonance imaging resulted in a diagnosis of Graves' disease and thymic hyperplasia. The thyroid function and thyroid-stimulating hormone receptor antibody (TRAb) were normalized one and five months after thiamazole initiation, respectively. The thymic size began to decrease after 1 month and was further decreased after 5 months; it was normalized after 12 months. The correlation between TRAb titers and the thymic size (R=0.99) suggested that the patient's autoimmunity might have contributed to the thymic hyperplasia.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556223 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.8710-21 | DOI Listing |
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