AI Article Synopsis
- * A study analyzing 160 liver transplant recipients found that factors like recipient BMI, heavy alcohol use by donors, and specific measurements during surgery (TEG MA) were linked to increased chances of needing a reoperation.
- * Addressing the combination of recipient obesity, heavy donor alcohol use, and low TEG MA may reduce the occurrence of these unplanned reoperations.
Article Abstract
Introduction: One in four liver transplants (LT) require return to the operating room(R-OR) within 48 h of surgery. We hypothesize that donor, recipient, and intraoperative factors will predict R-OR.
Methods: LT recipients were enrolled in an observational study to measure coagulation with thrombelastography (TEG) were assessed with transplant recipient and donor variables for risk of R-OR.
Results: 160 recipients with a median age of 55 years and a MELD-Na of 22 were analyzed. R-OR occurred in 22%. Recipient BMI (p = 0.006), donor heavy alcohol use (p = 0.017), TEG MA (p = 0.013) during the anhepatic phase of surgery, TEG MA at anhepatic and 30-min after reperfusion (p < 0.05), and red blood cell transfusions (p < 0.001) were associated with R-OR.
Conclusion: The vexing triad of recipient obesity, heavy donor alcohol use, and low TEG MA were associated with a high rate of R-OR. Strategies to reduce this sub-optimal combination of risk factors could reduce the frequency of unplanned re-operations.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580479 | PMC |
| http://dx.doi.org/10.1016/j.amjsurg.2022.02.053 | DOI Listing |
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