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DNA origami nanocalipers for pH sensing at the nanoscale. | LitMetric
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DNA origami nanocalipers for pH sensing at the nanoscale.

Xinyue Zhang Li Pan Ruiyan Guo Yueyue Zhang Fan Li Min Li Jiang Li Jiye Shi Fengli Qu Xiaolei Zuo Xiuhai Mao

Chem Commun (Camb)

Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.

Published: March 2022

A DNA origami nanocaliper is employed as a shape-resolved nanomechanical device, with pH-responsive triplex DNA integrated into the two arms. The shape transition of the nanocaliper results in a subtle difference depending on the local pH that is visible TEM imaging, demonstrating the potential of these nanocalipers to act as a universal platform for pH sensing at the nanoscale.

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 Source
http://dx.doi.org/10.1039/d1cc06701jDOI Listing

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