Henoch-Schönlein purpura (HSP) is a self-limited systemic vasculitis seen most commonly in paediatric group with multi organ involvements. We report a case of an infantile female who presented with cough, diarrhoea and vomiting. Two days later, she suddenly developed an erythematous, non-pruritic rash involving feet, thighs, buttocks and face; the lesion spared the trunk. Joints pain and swellings were also noticed. Coronavirus disease-19 Polymerase chain reaction (PCR) test was negative. She was diagnosed with HSP based on the American College of Rheumatology and European League Against Rheumatism, and Paediatric Rheumatology European Society criteria. The rash faded spontaneously within 2 weeks. We conclude that the careful skin examination is crucial for diagnosis of HSP.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879347PMC
http://dx.doi.org/10.24911/SJP.106-1614703471DOI Listing

Publication Analysis

Top Keywords

henoch-schönlein purpura
8
rheumatology european
8
atypical purpura
4
purpura location
4
location sudanese
4
sudanese infant
4
infant henoch-schönlein
4
purpura henoch-schönlein
4
purpura hsp
4
hsp self-limited
4

Similar Publications

We report the case of a 75-year-old woman who presented with fever, right back pain, paresthesia in the right extremities, erythema, purpura, and nodules. She had previously initiated dialysis due to rapidly progressive glomerulonephritis and was transferred to our hospital. Imaging studies revealed multiple cerebral and splenic infarcts and hemorrhage encapsulating the right kidney, likely due to microaneurysms in multiple renal arteries.

View Article and Find Full Text PDF

Congenital thrombotic thrombocytopenic purpura (cTTP) is a thrombotic microangiopathy (TMA) characterized by severe hereditary ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motifs 13) deficiency caused by mutations. This rare autosomal recessive genetic disorder is often misdiagnosed as immune thrombocytopenia (ITP) or hemolytic uremic syndrome (HUS). Here, we report a 21-year-old male cTTP patient with a compound heterozygous mutation.

View Article and Find Full Text PDF

Context: Osteonecrosis (ON) is bone death caused by inadequate blood supply and its optimal management remains uncertain.

Objective: We describe the outcomes of BP (pamidronate) treatment in our patients.

Design: Data regarding clinical, laboratory, magnetic resonance imaging (MRI) studies, and bone mineral density measurements (BMD) were recorded before and one year after treatment (reevaluation).

View Article and Find Full Text PDF

[Clinical analysis of 6 cases of induced rash and mucositis in children].

Zhonghua Er Ke Za Zhi

January 2025

Department of Gastroenterology and Infectious Diseases, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai200062, China.

To summarize the clinical features, laboratory findings, treatment and prognosis of children confirmed as -induced rash and mucositis (MIRM) in children. This retrospective study concluded 6 children diagnosed as MIRM in Department of Gastroenterology and Infectious Diseases, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University from August 2023 to April 2024. This paper described the characteristics of MIRM and analyzed the therapeutic strategy and prognosis.

View Article and Find Full Text PDF

A 35-year-old male with a history of hypertension presented with a thunderclap headache. Laboratory tests revealed isolated mild thrombocytopenia and plain brain imaging was normal. Subsequently he developed chest pain and breathlessness, accompanied with an acute kidney injury, elevated troponins and worsening thrombocytopenia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!