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Preferences and attitudes on acetate- versus lactate-buffered crystalloid solutions for intravenous fluid therapy-An international survey.
Acta Anaesthesiol Scand
January 2025
Department of Intensive Care, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Article Synopsis
- Clinical guidelines recommend using buffered crystalloid solutions for critically ill patients, but do not specify which type, prompting a survey of physicians' preferences between acetate- and lactate-buffered solutions.* -
- An international survey of 1321 anesthesiologists and ICU physicians found that the majority used these solutions frequently, with varying availability of both types across different countries.* -
- Most physicians supported a randomized trial comparing the two solutions, rating its clinical importance as significant, but not urgent, with a median score of 5 out of 9.*
Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial.
JAMA Pediatr
February 2023
Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Importance: Most children admitted to pediatric intensive care units (PICUs) receive intravenous fluids. A recent systematic review suggested mortality benefit in critically ill adults treated with balanced solutions compared with sodium chloride, 0.9% (saline).
View Article and Find Full Text PDFIssuing of isotonic crystalloid solutions to Danish public hospitals in 2021-A retrospective nationwide observational study.
Acta Anaesthesiol Scand
February 2023
Department of Intensive Care (4131), Copenhagen University Hospital, Copenhagen, Denmark.
Background: Intravenous (IV) fluid therapy is a ubiquitous intervention in daily clinical practice. However, nationwide detailed hospital- and departmental-level information on IV fluid use is limited. Hence, we aimed to describe the current issuing of isotonic crystalloid solutions across Danish public hospitals.
View Article and Find Full Text PDFAcetate- versus lactate-buffered crystalloid solutions: A systematic review with meta-analysis and trial sequential analysis.
Acta Anaesthesiol Scand
August 2022
Department of Intensive Care 4131, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Objective: There is a widespread use of buffered crystalloid solutions in clinical practice. However, guidelines do not distinguish between specific types of buffered solutions and clinical equipoise exists. We aimed to assess the desirable and undesirable effects of acetate- versus lactate-buffered solutions in hospitalised patients.
View Article and Find Full Text PDFAssessing mechanical catheter dysfunction in automated tidal peritoneal dialysis using cycler software: a case control, proof-of-concept study.
Sci Rep
April 2022
Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
New recommendations on evaluation of peritoneal membrane function suggest ruling out catheter dysfunction when evaluating patients with low ultrafiltration capacity. We introduce the use of a combination of parameters obtained from the cycler software PD Link with HomeChoicePro (Baxter International Inc., Illinois, United States) cyclers for predicting catheter dysfunction in automated peritoneal dialysis patients (APD).
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