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Latvian Healthcare Professionals' Self-Reported Knowledge, Attitudes, and Behaviors Related to Pregnancy Prevention Program Materials for Valproate-Containing Medicines.
Pharmacy (Basel)
December 2024
Department of Applied Pharmacy, Faculty of Pharmacy, LV-1007 Riga, Latvia and Institute of Public Health, Riga Stradiņš University, LV-1010 Riga, Latvia.
Background: Valproates are recognized for their significant teratogenic risks, which can lead to physical defects and developmental disorders when used during pregnancy. To mitigate these risks, the Pregnancy Prevention Program (PPP) was developed by European regulators for patients and healthcare professionals (HCPs). Despite the crucial nature of this program, the implementation of the PPP does not appear to be fully effective.
View Article and Find Full Text PDFUnderstanding Family Experiences: A Study on Mental Health Literacy in Adolescent Eating Disorder Diagnoses.
Nurs Rep
December 2024
School of Nursing, Fundación Jiménez Díaz, Madrid Autonomous University, 28049 Madrid, Spain.
Background: Adolescent eating disorders pose a significant public health challenge and strongly affect both physical and emotional well-being. Early diagnosis is important for improving treatment outcomes, though it remains complex due to multiple influencing factors. The family perspective is essential in this process, as it provides valuable insights into changes in adolescents' habits and emotional health.
View Article and Find Full Text PDFSide Effects of Novel Anticancer Drugs on the Posterior Segment of the Eye: A Review of the Literature.
J Pers Med
December 2024
Eye Unit, "Luigi Curto" Hospital, Azienda Sanitaria Locale Salerno, 84035 Polla, SA, Italy.
Currently, common treatment approaches for neoplastic diseases include surgery, radiation, and/or anticancer drugs (chemotherapy, hormone medications, and targeted therapies). In particular, anticancer medicines destroy cancerous cells by blocking certain pathways that aid in the disease's initiation and progression. These pharmaceutical drugs' capacity to inhibit malignant cells has made them indispensable in the treatment of neoplastic disorders.
View Article and Find Full Text PDFExploring Awareness Levels of Diabetic Ketoacidosis Risk Among Patients with Diabetes: A Cross-Sectional Study.
Clin Pract
December 2024
Center for Health Research, Northern Border University, Arar 91431, Saudi Arabia.
: Diabetic ketoacidosis (DKA) is a critical complication of diabetes mellitus, posing significant health. While global studies have indicated a concerning lack of awareness regarding DKA among patients with diabetes, research specific to the northern area of Saudi Arabia remains limited. This study aims to explore the level of knowledge and awareness of DKA among patients with diabetes residing in the local region.
View Article and Find Full Text PDFBiochemical characterization and mutational analysis of lysophosphatidic acid acyltransferases of Escherichia coli highlighting their involvement in the generation of membrane phospholipid diversity.
J Biochem
December 2024
Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.
Lysophosphatidic acid acyltransferase (LPAAT) is an enzyme responsible for the second acylation step of phospholipid biosynthesis and transforms lysophosphatidic acid to phosphatidic acid, a universal precursor of various phospholipids. In addition to the well-studied plsC-encoded LPAAT (EcPlsC), we previously found that Escherichia coli has another LPAAT that is encoded by yihG (EcYihG). EcPlsC and EcYihG are integral membrane proteins and have never been solubilized and purified in their active form.
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