AI Article Synopsis
- - Intellectual disability (ID) is a significant challenge for healthcare systems in developed countries.
- - There is a gap between what we know about the genes involved in ID and how these genetic changes lead to the disorder.
- - Understanding the disrupted signaling and transcriptional networks in ID can lead to new treatment options.
Article Abstract
Intellectual disability (ID) represents a major burden on healthcare systems in the developed world. However, there is a disconnect between our knowledge of genes that are mutated in ID and our understanding of the underpinning molecular mechanisms that cause these disorders. We argue that elucidating the signalling and transcriptional networks that are dysregulated in patients will afford new therapeutic opportunities.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10952735 | PMC |
| http://dx.doi.org/10.1111/febs.16411 | DOI Listing |
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