Background: Biliary adenofibroma (BF) is a rare benign epithelial tumor with the possibility of malignant transformation. Its main pathological feature is a well-defined cystic or honeycomb mass. BF has no specific clinical manifestations or laboratory and imaging findings; thus, it is easily misdiagnosed before surgery. This report describes a case in which biliary cystadenoma was misdiagnosed preoperatively and BF was diagnosed postoperatively. The imaging features, particularly the magnetic resonance imaging (MRI) features, were analyzed and summarized.

Case Summary: A 68-year-old Chinese man was admitted to our hospital with a 2-mo history of abdominal discomfort. Following admission to our hospital, laboratory examinations showed normal tumor marker concentrations and liver function. Hepatocellular carcinoma was considered after contrast-enhanced ultrasound examination. MRI suggested the possibility of cystadenoma of the bile duct. However, postoperative pathological examination confirmed the diagnosis of BF. No local recurrence was found 1 mo after surgery.

Conclusion: Our objective is to highlight the imaging diagnostic value of BF, especially on an MRI enhanced scan with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855190PMC
http://dx.doi.org/10.12998/wjcc.v10.i4.1366DOI Listing

Publication Analysis

Top Keywords

biliary adenofibroma
8
imaging
5
imaging presentation
4
presentation biliary
4
adenofibroma case
4
case report
4
report background
4
background biliary
4
adenofibroma rare
4
rare benign
4

Similar Publications

Article Synopsis
  • A study investigates a rare type of cholangiocarcinoma (CCA) with atypical histological features and adenofibromatous lesions, focusing on 8 biliary tumors.
  • The tumors exhibited a unique tubulocystic structure reminiscent of certain kidney cancers and were mostly found in older males and females, with a mean size of 4.4 cm and notable histological characteristics, including perineural invasion in one case.
  • Genetic analysis revealed shared mutations in chromatin remodeling genes and an actionable fusion gene, leading to the proposal of a new classification termed "tubulocystic carcinoma of bile ducts."
View Article and Find Full Text PDF

Biliary adenofibroma (BAF) is a rare benign tumor, but it has the potential for malignant transformation. The differentiation between benign and malignant forms of BAF before surgery is of great importance for clinical decision-making. We report a case of BAF with invasive carcinoma.

View Article and Find Full Text PDF

Biliary adenofibroma (BAF) is an uncommon liver tumor with a high propensity for malignant transformation. The histomorphology of BAF with malignant transformation can show a spectrum of changes ranging from benign, dysplastic to frank malignancy. Thus, the diagnosis of BAF imposes the pursuit of dysplasia/ malignancy focus.

View Article and Find Full Text PDF
Article Synopsis
  • Biliary adenofibroma is a rare benign liver tumor that can lead to malignancy, as evidenced by a case involving a 64-year-old woman who developed intrahepatic cholangiocarcinoma from it.
  • Imaging studies showed a 50 mm tumor with two distinct components, one resembling cholangiocarcinoma and the other fitting the description of biliary adenofibroma, requiring extended left hepatectomy for treatment.
  • Preoperative identification of biliary adenofibroma is difficult, highlighting the importance of detecting any malignant indicators during diagnosis.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!