Background: Biliary adenofibroma (BF) is a rare benign epithelial tumor with the possibility of malignant transformation. Its main pathological feature is a well-defined cystic or honeycomb mass. BF has no specific clinical manifestations or laboratory and imaging findings; thus, it is easily misdiagnosed before surgery. This report describes a case in which biliary cystadenoma was misdiagnosed preoperatively and BF was diagnosed postoperatively. The imaging features, particularly the magnetic resonance imaging (MRI) features, were analyzed and summarized.
Case Summary: A 68-year-old Chinese man was admitted to our hospital with a 2-mo history of abdominal discomfort. Following admission to our hospital, laboratory examinations showed normal tumor marker concentrations and liver function. Hepatocellular carcinoma was considered after contrast-enhanced ultrasound examination. MRI suggested the possibility of cystadenoma of the bile duct. However, postoperative pathological examination confirmed the diagnosis of BF. No local recurrence was found 1 mo after surgery.
Conclusion: Our objective is to highlight the imaging diagnostic value of BF, especially on an MRI enhanced scan with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid.
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http://dx.doi.org/10.12998/wjcc.v10.i4.1366 | DOI Listing |
Am J Surg Pathol
September 2024
Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona.
Cureus
January 2024
Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, CHN.
Biliary adenofibroma (BAF) is a rare benign tumor, but it has the potential for malignant transformation. The differentiation between benign and malignant forms of BAF before surgery is of great importance for clinical decision-making. We report a case of BAF with invasive carcinoma.
View Article and Find Full Text PDFUltraschall Med
February 2024
Division of Gastroenterology, University Hospital Leipzig, Leipzig, Germany.
Autops Case Rep
November 2023
Post Graduate Institute and Medical Education and Research, Department of General Surgery, Chandigarh, India.
Biliary adenofibroma (BAF) is an uncommon liver tumor with a high propensity for malignant transformation. The histomorphology of BAF with malignant transformation can show a spectrum of changes ranging from benign, dysplastic to frank malignancy. Thus, the diagnosis of BAF imposes the pursuit of dysplasia/ malignancy focus.
View Article and Find Full Text PDFAbdom Radiol (NY)
August 2023
Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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