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Deriving a Standardised Recommended Respiratory Disease Codelist Repository for Future Research. | LitMetric

AI Article Synopsis

  • Electronic health record (EHR) databases contain valuable data for researching respiratory conditions but face challenges due to inconsistent clinical coding.
  • A systematic search of literature and code repositories identified codelists for asthma, chronic obstructive pulmonary disease (COPD), and respiratory tract infections, revealing a limited number of studies included these codelists.
  • The study developed recommended codelists to help researchers access the most relevant and up-to-date information, highlighting the need for more consistent use of codelists across studies on respiratory diseases.

Article Abstract

Background: Electronic health record (EHR) databases provide rich, longitudinal data on interactions with healthcare providers and can be used to advance research into respiratory conditions. However, since these data are primarily collected to support health care delivery, clinical coding can be inconsistent, resulting in inherent challenges in using these data for research purposes.

Methods: We systematically searched existing international literature and UK code repositories to find respiratory disease codelists for asthma from January 2018, and chronic obstructive pulmonary disease and respiratory tract infections from January 2020, based on prior searches. Medline searches using key terms provided in article lists. Full-text articles, supplementary files, and reference lists were examined for codelists, and codelists repositories were searched. A reproducible methodology for codelists creation was developed with recommended lists for each disease created based on multidisciplinary expert opinion and previously published literature.

Results: Medline searches returned 1126 asthma articles, 70 COPD articles, and 90 respiratory infection articles, with 3%, 22% and 5% including codelists, respectively. Repository searching returned 12 asthma, 23 COPD, and 64 respiratory infection codelists. We have systematically compiled respiratory disease codelists and from these derived recommended lists for use by researchers to find the most up-to-date and relevant respiratory disease codelists that can be tailored to individual research questions.

Conclusion: Few published papers include codelists, and where published diverse codelists were used, even when answering similar research questions. Whilst some advances have been made, greater consistency and transparency across studies using routine data to study respiratory diseases are needed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859726PMC
http://dx.doi.org/10.2147/POR.S353400DOI Listing

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