AI Article Synopsis
- A systematic review and meta-analysis compared second-generation cryoballoon (2G-CB) ablation to contact force-sensing radiofrequency (CF-RF) ablation for treating paroxysmal atrial fibrillation (AF) and found no significant differences in success rates for freedom from atrial tachyarrhythmias (ATAs), freedom from AF, or acute pulmonary vein isolation (PVI).
- The 2G-CB ablation procedure took about 18.78 minutes less time than CF-RF ablation, but the fluoroscopy times were similar across both methods.
- However, patients undergoing 2G-CB ablation experienced a higher incidence of phrenic nerve paralysis, making the risks
Article Abstract
The superiority of second-generation cryoballoon (2G-CB) ablation versus contact force-sensing radiofrequency (CF-RF) ablation in patients with paroxysmal atrial fibrillation (AF) was assessed in this systematic review and meta-analysis. Freedom from atrial tachyarrhythmias (ATAs) (OR = 0.89; 95% confidence interval [CI] = 0.68 to 1.17; = 0.41), freedom from AF (OR = 0.93; 95% CI = 0.65 to 1.35; = 0.72), and acute pulmonary vein isolation (PVI) (OR = 1.17; 95% CI = 0.54 to 2.53; = 0.70) between 2G-CB ablation and CF-RF ablation were not different. The procedure time for the 2G-CB ablation was shorter (MD = -18.78 min; 95% CI = -27.72 to -9.85 min; < 0.01), while the fluoroscopy time was similar (MD = 2.66 min; 95% CI = -0.52 to 5.83 min; = 0.10). In the 2G-CB ablation group, phrenic nerve paralysis was more common (OR = 5.74; 95% CI = 1.80 to 18.31; = < 0.01). Regarding freedom from ATAs, freedom from AF, and acute PVI, these findings imply that 2G-CB ablation is not superior to CF-RF ablation in paroxysmal AF. Although faster than CF-RF ablation, 2G-CB ablation has a greater risk of phrenic nerve paralysis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876986 | PMC |
| http://dx.doi.org/10.3390/jpm12020298 | DOI Listing |
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Article Synopsis
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- However, patients undergoing 2G-CB ablation experienced a higher incidence of phrenic nerve paralysis, making the risks
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