Background: Gravid patients at high risk with placenta accreta spectrum (PAS) face life-threatening risk at delivery. Intraoperative risk assessment for patients is currently insufficient. We aimed to develop an assessment system of intraoperative risks through MRI-based radiomics.
Methods: A total of 131 patients enrolled were randomly grouped according to a ratio of 7:3. Clinical data were analyzed retrospectively. Radiomic features were extracted from sagittal Fast Imaging Employing State-sate Acquisition images. Univariate and multivariate regression analyses were performed to build models using R software. A receiver operating characteristic curve and decision curve analysis (DCA) were performed to determine the predictive performance of models.
Results: Six radiomic features and two clinical variables were used to construct the combined model for selection of removal protocols of the placenta, with an area under the curve (AUC) of 0.90 and 0.91 in the training and test cohorts, respectively. Nine radiomic features and two clinical variables were obtained to establish the combined model for prediction of intraoperative blood loss, with an AUC of 0.90 and 0.88 in the both cohorts, respectively. The DCA confirmed the clinical utility of the combined model.
Conclusion: The analysis of combined MRI-based radiomics with clinics could be clinically beneficial for patients.
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http://dx.doi.org/10.3390/diagnostics12020485 | DOI Listing |
Life (Basel)
November 2024
Third Surgical Clinic, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University of Padova, 35128 Padova, Italy.
Background: With rectum-sparing protocols becoming more common for rectal cancer treatment, this study aimed to predict the pathological complete response (pCR) to preoperative chemoradiotherapy (pCRT) in rectal cancer patients using pre-treatment MRI and a radiomics-based machine learning approach.
Methods: We divided MRI-data from 102 patients into a training cohort ( = 72) and a validation cohort ( = 30). In the training cohort, 52 patients were classified as non-responders and 20 as pCR based on histological results from total mesorectal excision.
Bioengineering (Basel)
November 2024
Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.
We assessed the feasibility of using deep learning-based image harmonization to improve the reproducibility of radiomics features in abdominal CT scans. In CT imaging, harmonization adjusts images from different institutions to ensure consistency despite variations in scanners and acquisition protocols. This process is essential because such differences can lead to variability in radiomics features, affecting reproducibility and accuracy.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA.
: Intracerebral hemorrhages (ICH) and perihematomal edema (PHE) are respective imaging markers of primary and secondary brain injury in hemorrhagic stroke. In this study, we explored the potential added value of PHE radiomic features for prognostication in ICH patients. : Using a multicentric trial cohort of acute supratentorial ICH ( = 852) patients, we extracted radiomic features from ICH and PHE lesions on admission non-contrast head CTs.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Biostatistics, Hacettepe University, 06230 Ankara, Türkiye.
Although COVID-19 is primarily known as a respiratory disease, there is growing evidence of neurological complications, such as ischemic stroke, in infected individuals. This study aims to evaluate the impact of COVID-19 on acute ischemic stroke (AIS) using radiomic features extracted from brain MR images and machine learning methods. This retrospective study included MRI data from 57 patients diagnosed with AIS who presented to the Department of Radiology at Hacettepe University Hospital between March 2020 and September 2021.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Machine and Hybrid Intelligence Lab, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Pancreatic cystic lesions (PCLs) represent a spectrum of non-neoplasms and neoplasms with varying malignant potential, posing significant challenges in diagnosis and management. While some PCLs are precursors to pancreatic cancer, others remain benign, necessitating accurate differentiation for optimal patient care. Conventional approaches to PCL management rely heavily on radiographic imaging, and endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA), coupled with clinical and biochemical data.
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