Background: Obstructive sleep apnea (OSA) and atrial fibrillation (AF) are known to often coexist together. However, whether all patients with AF should be screened for sleep abnormalities is not clear. No previous study has examined the association of asymptomatic OSA with AF.
Objective: This study sought to determine the prevalence of asymptomatic OSA in patients with persistent AF and whether asymptomatic OSA is an independent risk factor for atrial fibrillation.
Method: Patients with persistent AF without a prior diagnosis of OSA and asymptomatic for sleep abnormalities were prospectively enrolled over 12 months. All patients underwent polysomnography after informed consent. Patients without AF or OSA who underwent polysomnography during the same period served as controls.
Results: A total of 97 patients were studied; 50 were in the case group (patients with persistent AF) and 47 were in the control group (patients in sinus rhythm). Asymptomatic OSA was diagnosed on polysomnography in 72% of patients in the AF group and 17% of the control population. Multivariable analysis of factors including diabetes, hypertension, coronary artery disease, hypothyroidism, prior MI, and asymptomatic OSA, suggested asymptomatic OSA as an independent factor associated with AF.
Conclusion: A significant proportion (72%) of patients with persistent AF have underlying asymptomatic OSA. Sleep abnormality thus has a strong association with AF even in patients who are asymptomatic for OSA. Screening for OSA may be advised for all patients with AF, as this may have significant implications for management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091801 | PMC |
| http://dx.doi.org/10.1016/j.ipej.2022.02.018 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Retrospective longitudinal study on the long-term impact of COVID-19 infection on polysomnographic evaluation in patients with Prader-Willi syndrome.
Orphanet J Rare Dis
December 2024
Department of Paediatric Endocrinology and Diabetology, Children`s Hospital, University of Bonn, Venusberg Campus 1, Building 30, 53127, Bonn, Germany.
Background: To evaluate the impact of coronavirus disease 2019 (COVID-19) on polysomnographic evaluation in patients with Prader-Willi syndrome (PWS).
Patients And Methods: A retrospective cohort study of two consecutive overnight polysomnograms (PSG) in 92 PWS patients (mean age 9.1, range 3.
Altered cervical proprioception and biomechanics in obstructive sleep apnea: a case-control study.
Sleep Breath
November 2024
Department of Clinical Neurophysiology and Neurology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Purpose: This study aimed to compare cervical proprioception and related biomechanical factors among patients with Obstructive Sleep Apnea (OSA) and asymptomatic controls.
Methods: In this case-control study, polysomnography scores (apnea-hypopnea index-AHI) were examined to determine the disease severity of the OSA group. Also, we evaluated cervical proprioception by using a laser pointer to detect joint repositioning error sense in cervical rotational movements.
Calling for Action: The Need of Large-Scale Cohorts to Uncover the Cardiovascular Risk in Non-Sleepy Obstructive Sleep Apnea.
High Blood Press Cardiovasc Prev
October 2024
Department of Cardiovascular, Neural and Metabolic Sciences, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Article Synopsis
- Randomized clinical trials do not currently support using continuous positive airway pressure for treating asymptomatic obstructive sleep apnea (OSA), especially in low-risk patients.
- The OSCAR algorithm was proposed to help doctors manage asymptomatic moderate-severe OSA by focusing on weight loss, symptoms, and cardiovascular disease (CVD) risk.
- Research found no significant difference in the risk of major adverse cardiovascular events (MACE) between patients with moderate-severe OSA and those without OSA, indicating that more studies are needed on this topic.
Exploring the bidirectional relationship between sleep disorders and atrial fibrillation: implications for risk stratification and management.
Egypt Heart J
July 2024
Ivano Frankivsk National Medical University, Ivano Frankivsk, Ukraine.
Background: Atrial fibrillation (AF) is characterized by the absence of p-waves on ECG and irregular rhythm. It often presents with palpitations either palpitations may occur acutely over a short period or intermittently over several years. Other cardinal symptoms of atrial fibrillation include fatigue, dyspnea, and lightheadedness; it is important however to note that most affected individuals are asymptomatic.
View Article and Find Full Text PDFChronic obstructive pulmonary disease and obstructive sleep apnea overlap: who to treat and how?
Expert Rev Respir Med
July 2024
Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, California, USA.
Introduction: The co-existence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), or the overlap syndrome, is common and associated with a distinct pattern of nocturnal hypoxemia and worse clinical outcomes than either disease alone. Consequently, identifying who and how to treat these patients is essential.
Areas Covered: Treatment is recommended in all patients with OSA and symptoms or systemic hypertension, but determining symptoms attributable to OSA can be challenging in patients with COPD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!