AI Article Synopsis
- The study examines antipsychotic prescription trends among Japanese children and adolescents (≤17 years) in outpatient settings from 2006 to 2012, using a large dataset.
- It found that 65.1% of the patients were aged 13-17 and 52.9% were male, with an increase in second-generation antipsychotic monotherapy prescriptions from 53.8% to 78.3% during the study period.
- Risperidone was the most commonly prescribed drug, and about 25% of patients received initial doses that were lower than recommended.
Article Abstract
Little is known about antipsychotic prescription patterns among children and adolescents in Japan, particularly in outpatient settings. We investigated the prevalence and trends of antipsychotic prescription for outpatients aged ≤ 17 years receiving a first antipsychotic prescription from 2006 to 2012 based on a large-scale dispensation dataset. Measurements included age, sex, department of diagnosis and treatment, type of prescription (monotherapy or polytherapy), antipsychotic dosage, and concomitant psychotropic drugs. Of the 10,511 patients, 65.1% were aged 13-17 years, and 52.9% were males. Second-generation antipsychotic monotherapy prescriptions increased from 53.8% in 2006 to 78.3% in 2012. Risperidone was the most frequently prescribed antipsychotic, followed by aripiprazole and olanzapine. Approximately 25.0% of patients were prescribed an initial dose less than recommended. Second-generation antipsychotic monotherapy is currently the most frequent prescription pattern among outpatients aged ≤ 17 years receiving an initial antipsychotic prescription.
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| http://dx.doi.org/10.1007/s10578-022-01330-x | DOI Listing |
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