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Nanomaterials and clinical SERS technology: broad applications in disease diagnosis.
J Mater Chem B
January 2025
Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology, Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.
The critical need for rapid cancer diagnosis and related illnesses is growing alongside the current healthcare challenges, unfavorable prognosis, and constraints in diagnostic timing. As a result, emphasis on surface-enhanced Raman spectroscopy (SERS) diagnostic methods, including both label-free and labelled approaches, holds significant promise in fields such as analytical chemistry, biomedical science, and physics, due to the user-friendly nature of SERS. Over time, the SERS detection sensitivity and specificity with nanostructured materials for SERS applications (NMs-SERS) in different media have been remarkable.
View Article and Find Full Text PDFCharacterization of Optokinetic Nystagmus in Healthy Participants With a Novel Oculography Device.
Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.
Objective: To develop a proof-of-concept smart-phone-based eye-tracking algorithm to assess non-pathologic optokinetic (OKN) nystagmus in healthy participants. Current videonystagmography (VNG) is typically restricted to in-office use, and advances in portable vestibular diagnostics would yield immense public health benefits.
Study Design: Prospective cohort study.
Construction of Photosensitizer Candidates in Photodynamic Therapy: Computer Aided Design, Calculation, and Screening.
J Org Chem
January 2025
Institute of Theoretical Chemistry and College of Chemistry, Jilin University, Changchun 130023, P.R. China.
Thiophene and pyrrole units are extensively utilized in light-responsive materials and have significantly advanced the field of organic photovoltaics (OPV). This progress has inspired our exploration of photosensitizers (PS) for photodynamic therapy (PDT). Currently, traditional PS face limitations in clinical application, including a restricted variety and narrow applicability.
View Article and Find Full Text PDFThe graded heat-health risk forecast and early warning with full-season coverage across China: a predicting model development and evaluation study.
Lancet Reg Health West Pac
January 2025
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China.
Background: Due to global climate change, high temperature and heatwaves have become critical issues that pose a threat to human health. An effective early warning system is essential to mitigate the health risks associated with high temperature and heatwaves. However, most of the current heatwave early warning systems are not adequately developed based on the heat-health risk model, and the health impact of hot weather has not been well managed in most countries.
View Article and Find Full Text PDFThe Characteristics of the Metabolomic Profile in Patients with Parkinson's Disease and Vascular Parkinsonism.
Acta Naturae
January 2024
Novosibirsk State University, Novosibirsk, 630090 Russian Federation.
The gradually increasing age of the world population implies that the prevalence of neurodegenerative diseases also continues to rise. These diseases are characterized by a progressive loss of cognitive and motor functions. Parkinson's disease, which involves the gradual death of specialized neural tissue, is a striking example of a neurodegenerative process.
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