Three-dimensional direct laser writing based on a two-photon polymerization process of hybrid organic-inorganic material was used to print micrometer-scale refractive phase elements that were designed to manipulate incoming Gaussian beams into line and square intensity-flattened profiles. Here we present new results of shaping light beams, enabled by tailoring a two-photon absorption process for printing hybrid material structures based on a fast solgel process. The optical design and calculations of the optical elements are described, along with characterization of their performance in manipulating incoming light beams. The novelty described in this work, to the best of our knowledge, is the implementation of 3D solgel materials as better and improved micro-optics. This new ability provides upgraded 3D high resolution and smooth, printed optical phase structures using tailored hybrids with improved optical and mechanical properties compared to standard common photoresists. This opens new and exciting opportunities for compact and robust beam shaping by reaching glassy material properties and overcoming limitations of organic polymers.
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http://dx.doi.org/10.1364/AO.450931 | DOI Listing |
Optical neural implants allow neuroscientists to access deep brain regions, enabling to decipher complex patterns of neural activity. In this field, the use of optical fibers is rapidly increasing, and the ability to generate high-quality metal patterns on their non-planar surface would further extend their application. Here, we propose to use alternating metal shielding and dielectric confinement to engineer the mode-division properties of tapered optical fiber neural implants.
View Article and Find Full Text PDFSpecimen-induced aberrations limit the penetration depth of standard optical imaging techniques in vivo, mainly due to the propagation of high NA beams in a non-homogenous medium. Overcoming these limitations requires complex optical imaging systems and techniques. Implantable high NA micro-optics can be a solution to tissue induced spherical aberrations, but in order to be implanted, they need to have reduced complexity, offering a lower surface to the host immune reaction.
View Article and Find Full Text PDFBiosens Bioelectron
January 2025
Department of Electrical Engineering (ESAT-MNS), Catholic University of Leuven (KU Leuven), 3001, Leuven, Belgium; KU Leuven, Department of Physics and Astronomy (HF), Celestij€nenlaan 300D, 3001, Leuven, Belgium; Istituto Italiano di Tecnologia, Center for Biomolecular Nanotechnology, Arnesano, Italy.
Microneedles have emerged as a highly promising technology for advancing chemical biosensing and drug delivery applications, offering a minimally invasive, efficient, and versatile approach to healthcare innovation. This review provides a comprehensive analysis of photoresin-based microneedles, with a particular focus on SU-8 photoresin due to its favorable mechanical properties, biocompatibility, and ease of fabrication. Advanced techniques for surface modification are discussed to enhance the functionality of microneedles, enabling their application in precise biochemical diagnostics and effective drug therapy.
View Article and Find Full Text PDFAnnu Rev Biomed Eng
January 2025
1School of Engineering, Brown University, Providence, Rhode Island, USA;
The rise in popularity of two-photon polymerization (TPP) as an additive manufacturing technique has impacted many areas of science and engineering, particularly those related to biomedical applications. Compared with other fabrication methods used for biomedical applications, TPP offers 3D, nanometer-scale fabrication dexterity (free-form). Moreover, the existence of turnkey commercial systems has increased accessibility.
View Article and Find Full Text PDFMolecules
January 2025
College of Chemistry and Chemical Engineering, Central South University, Changsha 410017, China.
Ratiometric lanthanide coordination polymers (Ln-CPs) are advanced materials that combine the unique optical properties of lanthanide ions (e.g., Eu, Tb, Ce) with the structural flexibility and tunability of coordination polymers.
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