We present an experimental configuration for optical inspection of single vision soft contact lenses based on an active adaptive wavefront sensor. At first, the soft lenses were immersed in a saline filled wet cell to prevent surface deformation during measurements. Thereafter, refractive powers and aberrations were accurately measured before and after correcting illumination laser beam aberrations and wet cell-induced aberrations. The results reveal that there is a significant difference between the measured aberrations and refractive powers before and after aberration compensation. Accordingly, the proposed system is recommended as an optical inspection tool for precise assessment of commercially available contact lenses.
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http://dx.doi.org/10.1364/AO.441289 | DOI Listing |
Nat Commun
January 2025
Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA.
Optical aberrations hinder fluorescence microscopy of thick samples, reducing image signal, contrast, and resolution. Here we introduce a deep learning-based strategy for aberration compensation, improving image quality without slowing image acquisition, applying additional dose, or introducing more optics. Our method (i) introduces synthetic aberrations to images acquired on the shallow side of image stacks, making them resemble those acquired deeper into the volume and (ii) trains neural networks to reverse the effect of these aberrations.
View Article and Find Full Text PDFeNeuro
January 2025
Department of Cognitive and Brain Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Department of Computer Science, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Epilepsy, a neurological disorder characterized by recurrent unprovoked seizures, significantly impacts patient quality of life. Current classification methods focus primarily on clinical observations and electroencephalography (EEG) analysis, often overlooking the underlying dynamics driving seizures. This study uses surface EEG data to identify seizure transitions using a dynamical systems-based framework-the taxonomy of seizure dynamotypes-previously examined only in invasive data.
View Article and Find Full Text PDFCortex
December 2024
Department of Psychology, Sapienza University of Rome, Rome, Italy; IRCCS Fondazione Santa Lucia, Rome, Italy. Electronic address:
Binding, a critical cognitive process likely mediated by attention, is essential for creating coherent object representations within a scene. This process is vulnerable in individuals with dementia, who exhibit deficits in visual working memory (VWM) binding, primarily tested using abstract arrays of standalone objects. To explore how binding operates in more realistic settings across the lifespan, we examined the impact of object saliency and semantic consistency on VWM binding and the role of overt attention.
View Article and Find Full Text PDF3D Print Addit Manuf
October 2024
Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, China.
This article presents a fabrication strategy on the structural design, optimization, additive manufacturing, and processing of metal mirror. Specifically, the study showcases the topology design of a metal mirror with diameter of 200 mm, the additive manufacturing of standard aluminum-based powder (AlSi10Mg), the high-precision single-point diamond turning process of the surface. By setting the feasible domain partition, a topology optimization model suitable for metal additive manufacturing and subsequent surface shaping was constructed, which takes into account the multi-load machining load conditions of single-point diamond turning technology and the material topology representation of standard support structures for additive manufacturing.
View Article and Find Full Text PDF3D Print Addit Manuf
December 2024
Key Laboratory of Intelligent Manufacturing Technology (Shantou University), Ministry of Education, Shantou, China.
Cutting tools with orderly arranged diamond grits using additive manufacturing show better sharpness and longer service life than traditional diamond tools. A retractable needle jig with vacuum negative pressure was used to absorb and place grits in an orderly arranged manner. However, needle hole wear after a long service time could not promise complete grit adsorption forever.
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