Introduction: Oral cancer is a worldwide medical issue with expanding paces of occurrence and rising mortality rates. Oral cancer is the sixth most common cancer in Nepal with a prevalence of 4.6%. Examination of the oral cavity includes evaluating all teeth, supporting tissue, and surrounding oral tissue and recording the condition of these structures. The present study was conducted to find out the knowledge of oral cancer among general dental practitioners responding to a general survey.
Methods: A cross-sectional survey was conducted among general dental practitioners from March 2020 to July 2020 in 234 sample sizes. Convenience sampling technique was used. Data collection was done after taking ethical approval from the Institutional Review committee (Ref no. 10/020). Data collection was done using a self-administered questionnaire through Google forms. Data analysis was done using Statistical Package of the Social Sciences version 20 software.
Results: Our study showed that most of the participants i.e. 131 (56.2%) have moderately adequate knowledge about oral cancer. One-hundred and eighty four (78.6%) and 178 (76.1%) identified smokeless tobacco and smoking tobacco as high-risk factors for oral cancer. Two-hundred (85.5%) participants recognised buccal/labial mucosa as a common site for oral cancer. And, 138 (59.2%) have knowledge about early detection of oral cancer.
Conclusions: Our study highlights that general dentists have moderate knowledge regarding oral cancer and. Study also states that more practical knowledge and training should be included in undergraduate programs.
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http://dx.doi.org/10.31729/jnma.5651 | DOI Listing |
Adv Sci (Weinh)
December 2024
Laboratory of Precision Nanomedicine, The Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Squamous cell carcinomas of the head and neck (HNSCC) originate in the upper aerodigestive tract, including the oral cavity, pharynx, and larynx. Current treatments of locally advanced HNSCC often lead to high treatment failure, and disease recurrence, resulting in poor survival rates. Advances in mRNA technologies and lipid nanoparticle (LNP) delivery systems led to several clinical trials involving LNP-CRISPR-Cas9 mRNA-based therapeutics.
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January 2024
Department of Chest Diseases, School of Medicine, Hacettepe University, Ankara, Turkey.
remains a global public health issue. Although predominantly affecting the liver, the lungs are the second most affected organ and often undergo surgical intervention. Here, a case managed by bronchoscopy and medical therapy is presented.
View Article and Find Full Text PDFCureus
November 2024
Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, IND.
Introduction Oral verrucous carcinoma (OVC), a low-grade variation of oral squamous cell carcinoma (OSCC), is distinguished by endophytic development and a pebbly, mammillated surface. OVC, often referred to as Ackerman's tumor, has been known to involve lymph nodes but rarely spreads to regional and distant locations; when the primary tumor grows, it frequently involves surrounding tissues. Histopathologically, it has a thicker basement membrane, many reduplications, and a large area of inflammatory infiltration that resembles OSCC.
View Article and Find Full Text PDFCureus
November 2024
Department of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Background Determining good candidates for head and neck cancer surgery in elderly patients requires consideration of various factors, such as overall health and social background, yet specific evaluation guidelines are lacking. The Glasgow Prognostic Score (GPS) is a marker used to assess nutritional status and prognosis in cancer patients. Objective This study aims to evaluate the association between the GPS and both the prognosis and postoperative complications in reconstructive surgery cases for head and neck cancer in patients aged 80 and over.
View Article and Find Full Text PDFBioact Mater
April 2025
Department of Oral and Cranio-maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stom, Shanghai, 200011, China.
Angiogenesis is imperative for bone regeneration, yet the conventional cytokine therapies have been constrained by prohibitive costs and safety apprehensions. It is urgent to develop a safer and more efficient therapeutic alternative. Herein, utilizing the methodologies of Deep Learning (DL) and Natural Language Processing (NLP), we proposed a paradigm algorithm that amalgamates with a variant, , to deftly discern potential pro-angiogenic peptides from intrinsically disordered regions (IDRs) of 262 related proteins, where are fertile grounds for developing safer and highly promising bioactive peptides.
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