AI Article Synopsis

  • Women face distinct sex- and gender-related risk factors for cardiovascular disease (CVD) that change throughout their lives, including conditions like pregnancy complications and menopause.
  • Autoimmune disorders are more common in women and contribute to their increased risk of CVD, while traditional risk factors like obesity and hypertension affect women more severely than men.
  • The chapter aims to identify these unique risk factors and improve understanding and treatment strategies for CVD in women.

Article Abstract

Women have unique sex- and gender-related risk factors for cardiovascular disease (CVD) that can present or evolve over their lifespan. Pregnancy-associated conditions, polycystic ovarian syndrome, and menopause can increase a woman's risk of CVD. Women are at greater risk for autoimmune rheumatic disorders, which play a role in the predisposition and pathogenesis of CVD. The influence of traditional CVD risk factors (eg, smoking, hypertension, diabetes, obesity, physical inactivity, depression, anxiety, and family history) is greater in women than men. Finally, there are sex differences in the response to treatments for CVD risk and comorbid disease processes. In this Atlas chapter we review sex- and gender-unique CVD risk factors that can occur across a woman's lifespan, with the aim to reduce knowledge gaps and guide the development of optimal strategies for awareness and treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843896PMC
http://dx.doi.org/10.1016/j.cjco.2021.09.013DOI Listing

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