The combination of sleep deprivation, sleep phase advance, and bright light is termed triple chronotherapy (TCT). TCT is a promising treatment for depression, but it is not clear how effective it is for depression resistant to conventional treatments such as medications. Here, we report a case of triple chronotherapy effectively treating depression resistant to both medication and an extended course of bilateral electroconvulsive therapy. Triple chronotherapy may be a useful method to consider in cases of severe, treatment-resistant depression.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860525 | PMC |
| http://dx.doi.org/10.1155/2022/9957190 | DOI Listing |
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