Background: Breast reduction is a time-consuming procedure with a relatively high complication rate. Furthermore, recurrent breast enlargement can occur in case of postoperative weight gain. The authors describe a breast reduction technique based on liposuction, followed mostly by skin resection alone, which makes this operation easier, faster, and safer, with more stable results.
Methods: Two hundred thirty-three patients were treated by breast liporeduction between 2006 and 2017, with an age range of 18 to 70 years (average age, 42 years). The patients were selected after careful clinical and instrumental assessment among those in whose breasts the fat component was prevalent over the gland. Most of the soft-tissue reduction consisted of fat aspiration. The follow-up ranged from 12 months to 9 years (average, 4.5 years).
Results: The results of this study have been extremely satisfactory. Most of the patients healed uneventfully and were happy with the final outcome. Very few complications were encountered, among which were small steatonecroses and partial nipple-areola complex necroses.
Conclusions: For the past 15 years, all four authors have preferred this breast reduction technique over others. Fat only is selectively removed by aspiration with a blunt cannula, sparing the vascular network and easily mobilizing the nipple-areola complex. Liporeduction provides a good stable result because any postoperative weight variation will not change the volume of a breast consisting mainly of glandular and fibrous tissue.
Clinical Question/level Of Evidence: Therapeutic, IV.
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http://dx.doi.org/10.1097/PRS.0000000000008876 | DOI Listing |
J Gynecol Obstet Hum Reprod
December 2024
Assistance Publique-Hospitals of Paris, Department of Gynecological and Breast Surgery and Oncology, Pitié Salpêtrière Hospital, Paris, France; University Institute of Cancer (IUC), AP-HP, Sorbonne University, Paris, France; Saint-Antoine Research Center (CRSA), INSERM UMR_S_938, Biology and Therapeutics of Cancer, Sorbonne University, Paris, France. Electronic address:
Introduction: Fibroids are the most common benign uterine tumors. There are different possibilities for surgical approaches, and evaluating the cost of these operations is fundamental in modern surgery. The aim of our study is to evaluate the cost-effectiveness of robotic-assisted myomectomy (RAM) compared to open myomectomy (OM) in France.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
November 2024
Department of Biology, Faculty of Science, İstanbul University, Istanbul, Turkiye.
The increasing incidence of cancer has necessitated the discovery of novel anticancer compound sources. The presence of taxanes in hazelnut cell cultures has promoted new promising pharmacotherapeutic applications. The antiproliferative properties of hazelnut (Corylus avellana cv.
View Article and Find Full Text PDFCancer Lett
December 2024
Department of Neurology, University of California Irvine, Irvine, CA, USA; Department of Pathology, University of California Irvine, Irvine, CA, USA; Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA. Electronic address:
Cancer-related cognitive impairment (CRCI) is prevalent among cancer patients. A critical disparity in the CRCI field is that most pre-clinical studies have been conducted on young cancer-free male rodents, although CRCI predominantly affects breast cancer and ovarian cancer women survivors. Since oxidative stress is widely implicated in the development of CRCI, we developed an ovarian cancer xenograft rat model of CRCI in Cr:NIH-RNU female rats to examine whether administration of the antioxidant N-acetylcysteine (NAC) prevents cisplatin-induced CRCI without altering its anti-cancer efficacy.
View Article and Find Full Text PDFBr J Radiol
December 2024
Department of Oncology, Nottingham University Hospitals NHS Trust, City Hospital, Hucknall Road, Nottingham, NG5 1PB.
Objectives: To audit prospectively the accuracy, time saving and utility of a commercial artificial intelligence auto-contouring tool (AIAC). To assess the reallocation of time released by AIAC.
Methods: We audited the perceived usefulness (PU), clinical acceptability and reallocation of time during the introduction of a commercial AIAC.
Ther Adv Drug Saf
December 2024
The Center of Breast Disease Diagnosis and Treatment of Affiliated Hospital of Qinghai University and Affiliated Cancer Hospital of Qinghai University, No. 29 Tongren Road, Xining, Qinghai 810000, China.
Background: Antibody-drug conjugates (ADCs), as a new type of targeted drug, have been widely used in breast cancer patients in recent years. However, while achieving better efficacy, its hepatotoxicity should not be ignored.
Objectives: To clarify the incidence of hepatotoxicity associated with ADCs and compare the incidence of hepatotoxicity of ADCs with different drugs.
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