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| http://dx.doi.org/10.1164/rccm.202201-0006ED | DOI Listing |
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Evolved and Plastic Gene Expression in Adaptation of a Specialist Fly to a Novel Niche.
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Department of Biology, Lund University, Lund, Sweden.
How gene expression evolves to enable divergent ecological adaptation and how changes in gene expression relate to genomic architecture are pressing questions for understanding the mechanisms enabling adaptation and ecological speciation. Furthermore, how plasticity in gene expression can both contribute to and be affected by the process of ecological adaptation is crucial to understanding gene expression evolution, colonisation of novel niches and response to rapid environmental change. Here, we investigate the role of constitutive and plastic gene expression differences between host races, or host-specific ecotypes, of the peacock fly Tephritis conura, a thistle bud specialist.
View Article and Find Full Text PDFThe Effects of Socioeconomic Contextual Factors on Racial Differences in CFSR-3 Permanency Outcomes.
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Chapin Hall, Chicago, IL, USA.
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African American (AA) women are twice as likely to develop triple-negative breast cancer (TNBC) as women of European descent. Additionally, AA women with TNBC present a much more aggressive disease course than their European American (EA) counterparts. Thus, there is an unmet clinical need to identify race-specific biomarkers and improve survival outcomes in AA patients with TNBC.
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