Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/DSS.0000000000003373 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Successful Management of Palatal Developmental Groove-Associated Periodontal Defect Using Palatal Access Flap and Odontoradiculoplasty: A Case Report.
Case Rep Dent
January 2025
Department of Surgical Sciences, Division of Conservative Dentistry and Endodontics, School of Dental Medicine, University of Cagliari, Cagliari, Italy.
This case report discusses the successful management of a deep palatal developmental groove associated with Stage III generalized Grade C periodontitis. Despite prior nonsurgical periodontal therapy, the disease progressed rapidly, necessitating further intervention. A comprehensive evaluation revealed generalized periodontitis with localized tooth-related predisposing factor due to a developmental groove in the vital upper left lateral incisor.
View Article and Find Full Text PDFDiverse Interactions of Sterols with Amyloid Precursor Protein Transmembrane Domain Can Shift Distribution Between Alternative Amyloid-β Production Cascades in Manner Dependent on Local Lipid Environment.
Int J Mol Sci
January 2025
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Alzheimer's disease (AD) pathogenesis is correlated with the membrane content of various lipid species, including cholesterol, whose interactions with amyloid precursor protein (APP) have been extensively explored. Amyloid-β peptides triggering AD are products of APP cleavage by secretases, which differ depending on the APP and secretase location relative to ordered or disordered membrane microdomains. We used high-resolution NMR to probe the interactions of the cholesterol analog with APP transmembrane domain in two membrane-mimicking systems resembling ordered or perturbed lipid environments (bicelles/micelles).
View Article and Find Full Text PDFEngineering a Novel NIR RNA-Specific Probe for Tracking Stress Granule Dynamics in Living Cells.
Anal Chem
January 2025
Institute of Physical Science and Information Technology, Information Materials and Intelligent Sensing Laboratory of Anhui Province, Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, Anhui 230601, China.
Real-time monitoring of the dynamics of cytosolic RNA-protein condensates, termed stress granules (SGs), is vital for understanding their biological roles in stress response and related disease treatment but is challenging due to the lack of simple and accurate methods. Compared with protein visualization that requires complex transfection procedures, direct RNA labeling offers an ideal alternative for tracking SG dynamics in living cells. Here, we propose a novel molecular design strategy to construct a near-infrared RNA-specific fluorescent probe () for tracking SGs in living cells.
View Article and Find Full Text PDFInsights into interaction of quaternary ammonium salt cationic surfactants with different branched-chain lengths and DNA: Multi-spectral analysis, viscosity method, and gel electrophoresis.
Int J Biol Macromol
January 2025
School of Chemistry, Liaoning University, Shenyang 110036, China. Electronic address:
In this study, the interactions between three quaternary ammonium salt (QAS) cationic surfactants with different branched-chain lengths (TMBAC, TEBAC, and TBBAC) and DNA are investigated by UV-vis absorption, fluorescence and CD spectroscopy, viscosity method, and gel electrophoresis. Berberine hydrochloride (BR) is utilized as a fluorescent probe. The three interaction modes and strengths are compared.
View Article and Find Full Text PDFBLV-CoCoMo Dual qPCR Assay Targeting LTR Region for Quantifying Bovine Leukemia Virus: Comparison with Multiplex Real-Time qPCR Assay Targeting Region.
Pathogens
December 2024
Laboratory of Global Infectious Diseases Control Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
The proviral load (PVL) of the bovine leukemia virus (BLV) is a useful index for estimating disease progression and transmission risk. Real-time quantitative PCR techniques are widely used for PVL quantification. We previously developed a dual-target detection method, the "Liquid Dual-CoCoMo assay", that uses the coordination of common motif (CoCoMo) degenerate primers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!