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http://dx.doi.org/10.1186/s12992-022-00816-6 | DOI Listing |
BMC Oral Health
January 2025
Division of Fixed Prosthodontics, Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Background: Increasing demand for durable and aesthetically pleasing dental restorations, including laminates, inlays, onlays, and crowns, has led to advancements in all-ceramic systems, particularly with the development of advanced lithium disilicate materials. However, limited data on the fit accuracy and fracture resistance of these materials restricts their wider application in clinical restorative practices.
Aim Of The Study: This in vitro study aims to compare the marginal and internal fit, assess the fracture resistance, and evaluate the failure modes of crowns fabricated from advanced and conventional lithium disilicate materials.
BMC Oral Health
January 2025
Department of Conservative Dentistry, College of Dentistry, Kyung Hee University, 26-6, Kyungheedae-ro, Dongdaemun-gu, Seoul, 02453, Republic of Korea.
Background: This study aims to compare design, phase transformation behavior, and torsional resistance of the ProGlider (PG) and ProTaper ultimate slider (PUS) and to compare the performance of two files in the glide-path preparation of a double-curved artificial canal.
Methods: Scanning electron microscopy, micro-computed tomography, and differential scanning calorimetry were used to characterize the samples. A torsional resistance test was performed to obtain ultimate strength and distortion angle.
Sci Rep
January 2025
Department of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, 34140, Turkey.
This is the first study to evaluate the adequacy and reliability of the ChatGPT and Gemini chatbots on viral hepatitis. A total of 176 questions were composed from three different categories. The first group includes "questions and answers (Q&As) for the public" determined by the Centers for Disease Control and Prevention (CDC).
View Article and Find Full Text PDFAm J Geriatr Psychiatry
December 2024
Department of Clinical and Experimental Sciences (DA, BB), University of Brescia, Brescia, Italy; Molecular Markers Laboratory (BB), IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy. Electronic address:
Objectives: The present study aims to assess the prevalence, associated clinical symptoms, longitudinal changes, and imaging correlates of Loss of Insight (LOI), which is still unexplored in syndromes associated with Frontotemporal Lobar Degeneration (FTLD).
Design: Retrospective longitudinal cohort study, from Oct 2009 to Feb 2023.
Setting: Tertiary Frontotemporal Dementia research clinic.
J Hepatol
January 2025
MASLD Research Center, Division of Gastroenterology and Hepatology, University of California at San Diego, La Jolla, CA, USA.
Background & Aims: A common genetic variant (rs738409) encoding isoleucine to methionine at position 148 in the PNPLA3 protein is a determinant of hepatic steatosis, inflammation, fibrosis, cirrhosis, and liver-related mortality. AZD2693 is a liver-targeted antisense oligonucleotide against PNPLA3 mRNA. We evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics in single ascending dose (SAD) and multiple ascending dose (MAD) studies.
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