Organophosphates (OPEs) are manmade organic pollutants that are widely used as flame retardants, plasticizers, and antifoaming and hydraulic agents. In this study, seven OPEs in seawater and sediment from the Yellow Sea and East China Sea were determined to study the distribution and diffusion behavior, and to evaluate the environmental risks. The ΣOPEs in the seawater and sediments ranged from below the method detection limit (
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http://dx.doi.org/10.1016/j.envpol.2022.119017 | DOI Listing |
Metabolites
December 2024
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, Bisha 61922, Saudi Arabia.
TCIPP (tris(1,3-dichloro-2-propyl) phosphate) and TCEP (tris(2-chloroethyl) phosphate) are organophosphate ester flame retardants found in various consumer products, posing significant health and environmental risks through inhalation, ingestion, and dermal exposure. Research reveals these compounds cause oxidative stress, inflammation, endocrine disruption, genotoxicity, neurotoxicity, and potentially hepatotoxicity, nephrotoxicity, cardiotoxicity, developmental, reproductive, and immunotoxicity. This review summarizes the current knowledge on the toxicological mechanisms of TCIPP and TCEP and presents the latest data on their toxicological effects obtained in vitro and in vivo, using omic systems, and on the basis of computational modelling.
View Article and Find Full Text PDFChemosphere
December 2024
Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, 08034 Barcelona, Spain. Electronic address:
The assessment of persistence of organic pollutants in seawater is limited by the lack of user-friendly, quick protocols for assessing one of their main sinks, degradation by marine bacteria. Here we present an experimental workflow to identify organic pollutants degradation, taking organophosphate esters flame retardants and plasticizers (OPEs-FR-PL), as a model family of synthetic chemicals released into the marine environment that are particularly widespread due to their persistence and semi-volatile nature. The proposed novel workflow combines culture-dependent techniques, solvent demulsification-dispersive liquid-liquid microextraction, with quantitative liquid chromatography coupled with mass spectrometry analyses in order to identify marine bacterial isolates with the potential to degrade OPEs-FR-PL in the marine environment.
View Article and Find Full Text PDFEnviron Sci Technol
December 2024
MOE Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.
Industrial activities are a major source of organophosphorus flame retardants (OPFRs) and plasticizers in aquatic environments. This study investigated the distribution of 40 OPFRs in a river impacted by major industrial manufacturing plants in Eastern China by target analysis. Nontarget analysis using high-resolution mass spectrometry was further employed to identify novel organophosphorus compounds (NOPs).
View Article and Find Full Text PDFToxicology
December 2024
Helmholtz Centre for Environmental Research - UFZ, Department Ecotoxicology, Leipzig, Germany; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels-Belgium.
Novel flame retardants (NFRs) have emerged as chemicals of environmental health concern due to their widespread use as an alternative to polybrominated diphenyl ethers (PBDE) in electrical and electronic devices. Humans and ecosystems are under threat because of e-waste recycling procedures that may emit NFRs and other anthropogenic chemicals into the e-waste workplace and the surrounding environment. The individual toxicity of NFRs including novel brominated flame retardants (NBFRs), their combined effects and the underlying mechanisms of toxicity have remained poorly understood.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Textile Science and Engineering (International Institute of Silk Institute), Zhejiang Sci-Tech University, Hangzhou 310018, China. Electronic address:
Developing eco-friendly and effective flame retardants is crucial for enhancing the fire resistance of polymeric materials. This study developed a novel nitrogen‑phosphorus (NP) synergistic nanocellulose-based flame retardant (CNC-PEI-PA) by grafting polyethyleneimine (PEI) and phytic acid (PA) onto the CNC. CNC-PEI-PA demonstrated remarkable thermal stability, char-forming ability, and antibacterial activity.
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