Pseudokinases are critical signaling hubs that are increasingly appreciated as important disease targets. In this issue of , Hou bring new insights into the signaling mechanisms of the pseudokinase PEAK3 by characterizing its epidermal growth factor-dependent interactome and demonstrating oncogenic effects of PEAK3 overexpression.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288111 | PMC |
http://dx.doi.org/10.1126/scisignal.abm9396 | DOI Listing |
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