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| http://dx.doi.org/10.1097/CM9.0000000000002013 | DOI Listing |
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Bronchoscopic lung volume reduction complicated by ipsilateral pleural effusion.
Respir Med Case Rep
December 2024
Section of Pulmonary, Critical Care and Sleep Medicine Carilion Clinic, Virginia Tech School of Medicine, USA.
Chronic obstructive lung disease is the third leading cause of death worldwide. It affects the airways and lung parenchyma leading to emphysema. Bronchoscopic lung volume reduction is another strategy that aims to reduce air trapping and hyperinflation, leading to improvement in symptoms and pulmonary function.
View Article and Find Full Text PDFFecal microbiota transplantation in severe pneumonia: a case report on overcoming pan-drug resistant infection.
Front Med (Lausanne)
December 2024
Department of Respiratory and Critical Care Medicine, Fuzong Clinical Medical College of Fujian Medical University, Dongfang Hospital of Xiamen University, The 900th Hospital of Joint Logistics Support Force, Fuzhou, China.
Objective: To evaluate the therapeutic potential of fecal microbiota transplantation (FMT) in treating severe pneumonia patients with concurrent pan-drug resistant infection.
Methods: A case report of a 95-year-old female patient with severe pneumonia, complicated by pan-resistant bacterial infections, is presented. The patient was diagnosed with severe pneumonia caused by COVID-19, along with co-infections of , , , , ESBL-producing pan-drug resistant and pan-resistant .
Surgical and Bronchoscopic Lung Volume Reduction for Severe Emphysema: A Systematic Review and Network Meta-analysis.
Lung
January 2025
Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
Article Synopsis
- The systematic review examines surgical and bronchoscopic options for lung volume reduction in patients with severe emphysema, comparing their effectiveness and associated risks.
- It includes data from 25 randomized controlled trials involving over 4,000 patients, revealing that lung volume reduction surgery (LVRS) led to significant improvements in lung function and exercise capacity but also increased mid-term mortality risks.
- The findings suggest that while endobronchial valve (EBV) and endobronchial coil (EBC) procedures showed notable benefits similar to LVRS in lung function improvements, they also carry a higher risk of pneumothorax and slightly increased mortality, highlighting the need for further long-term survival studies for bronchoscopic interventions.
Epithelial stem cells from human small bronchi offer a potential for therapy of idiopathic pulmonary fibrosis.
EBioMedicine
January 2025
Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. Electronic address:
Background: Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial pneumonia with restrictive ventilation. Recently, the structural and functional defects of small airways have received attention in the early pathogenesis of IPF. This study aimed to elucidate the characteristics of small airway epithelial dysfunction in patients with IPF and explore novel therapeutic interventions to impede IPF progression by targeting the dysfunctional small airways.
View Article and Find Full Text PDFBronchoscopic Closure of Bronchopleural Fistula with Occluder.
Cancer Manag Res
December 2024
Department of Pulmonary and Critical Care Medicine, the Affiliated Hospital of Yunnan Medical University, Key Laboratory of Respiratory Disease Research of Department of Education of Yunnan Province, Kunming, 650021, People's Republic of China.
Bronchopleural Fistula (BPF) represents one of the gravest complications post-lobectomy. Present treatment strategies encompass a wide array of surgical techniques complemented by essential adjunct therapies. Despite numerous treatment modalities, mortality rates associated with BPF remain disconcertingly high.
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