Immunostimulatory effects of radioimmunotherapy.

J Immunother Cancer

Institut de Recherche en Cancérologie de Montpellier (IRCM), INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier (ICM), Montpellier, France.

Published: February 2022

Radiation therapy (RT) is known for its ability to kill cancer cells in an immunogenic manner. Recent preclinical data demonstrate that targeted alpha-particle therapy shares with RT the capacity to elicit immunostimulatory effects, standing out as a promising strategy to circumvent immune checkpoint inhibitor resistance in immunologically 'cold' tumors.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862476PMC
http://dx.doi.org/10.1136/jitc-2021-004403DOI Listing

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